Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a multicenter, randomized, controlled trial

Enrique Soto, Soto E, Luu TH, Thanh Ha Luu, Liu X, Xiaobo Liu, Magrina JF, Javier F Magrina, Megan Wasson, Megan N Wasson, Einarsson JI, Jon I Einarsson, Cohen SL, Sarah L Cohen, Falcone T, Tommaso Falcone
Fertility and sterility · 2017 · vol. 107(4) , pp. 996–1002.e3 · doi:10.1016/j.fertnstert.2016.12.033 · PMID:28238489 · W2589501886
article OA: bronze CC0 ⤵ 79 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This randomized controlled trial compared laparoscopic and robotic surgery outcomes for endometriosis treatment across multiple centers.

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Abstract

ObjectiveTo determine whether the use of the robot for surgical treatment of endometriosis is better than traditional laparoscopy in terms of operative length, perioperative parameters, and quality of life outcomes.DesignMulticenter, randomized clinical trial.SettingUniversity teaching hospitals.Patient(s)Women aged >18 years with suspected endometriosis who elected to undergo surgical management.Intervention(s)Randomization to conventional or robot-assisted laparoscopic removal of endometriosis.Main outcome measure(s)The primary outcome measured was operative time. Secondary outcomes were perioperative complications and quality of life.Result(s)The mean operative time for robotic vs. laparoscopic surgery for endometriosis was 106.6 ± 48.4 minutes vs. 101.6 ± 63.2 minutes. There were no differences in blood loss, intraoperative or postoperative complications, or rates of conversion to laparotomy in the two arms. Both groups reported significant improvement on condition-specific quality of life outcomes at 6 weeks and 6 months.Conclusion(s)There were no differences in perioperative outcomes between robotic and conventional laparoscopy.Clinical trial registration numberNCT01556204.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Laparoscopy Laparoscopy Robotic Surgical Procedures Robotic Surgical Procedures Adult Blood Loss, Surgical Conversion to Open Surgery Endometriosis Endometriosis Female Hospitals, University Humans Operative Time Postoperative Complications Postoperative Complications Prospective Studies Quality of Life Time Factors Treatment Outcome

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