Peritoneal fluid concentrations of interleukin‐17 correlate with the severity of endometriosis and infertility of this disorder

Xinmei Zhang, Hong Xu, Jun Lin, Yuli Qian, Lin Deng
BJOG: An International Journal of Obstetrics & Gynaecology · 2005 · vol. 112(8) , pp. 1153–1155 · doi:10.1111/j.1471-0528.2005.00639.x · PMID:16045534 · W2060196904
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study found higher peritoneal fluid interleukin-17 in patients with minimal/mild endometriosis and when endometriosis coexists with infertility, suggesting IL-17's role in early disease and associated infertility.

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Abstract

This prospective study aimed to determine whether patients with endometriosis are having different level of interlukin-17 (IL-17) in peritoneal fluid when compared with patients without endometriosis. The patients with minimal/mild endometriosis had a significantly higher level of IL-17 in peritoneal fluid compared with those with moderate/severe endometriosis or without endometriosis. The concentration of IL-17 in peritoneal fluid was significantly higher when endometriosis and infertility coexist. However, the concentration of IL-17 in peritoneal fluid did not correlate with the phase of the menstrual cycle in the patients with or without endometriosis. Our study suggested that IL-17 might play an important role in the pathogenesis of early endometriosis and endometriosis-associated infertility.

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Condition tags

mesh:D004715endometriosisinfertility

MeSH descriptors

Ascitic Fluid Endometriosis Infertility, Female Interleukin-17 Abdominal Pain Abdominal Pain Adult Ascitic Fluid Case-Control Studies Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Interleukin-17 Menstrual Cycle Menstrual Cycle Prospective Studies

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (7)

Cited by (50)

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