Antiendometrial Antibodies in Patients With Endometriosis

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AI-generated summary by claude@2026-06, 2026-06-08

This study evaluated serum antiendometrial antibodies in infertile patients, finding that 85.7% of those with positive antibody tests also had endometriosis, suggesting a potential for an immunological diagnostic test.

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Abstract

Sera from 42 patients complaining of infertility were evaluated by indirect immunofluorescence for the presence of antibodies to the endometrium. The presence or absence of antibodies was matched with the findings at laparoscopy. Of the 42 patients examined for infertility, 28 (66.7%) had laparoscopic findings that corresponded to the presence or absence of endometriosis. Of 28 patients with positive antibody tests, 24 (85.7%) were found to have endometriosis. No correlation between the degree of immunofluorescence and the clinical severity of endometriosis could be determined. These findings suggest the possibility of developing a noninvasive immunological test for the presence of endometriosis.

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Condition tags

endometriosisinfertility

MeSH descriptors

Autoantibodies Endometriosis Endometrium Infertility, Female Autoantibodies Autoimmune Diseases Autoimmune Diseases Endometriosis Endometriosis Endometriosis Endometrium Female Fluorescent Antibody Technique Humans Infertility, Female Infertility, Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (17)

Cited by (50)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:09:45.632124+00:00
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