Antiendometrial antibodies in patients with endometriosis

R A Wild, Robert A. Wild, Wild RA, C A Shivers, Charles Alex Shivers, Shivers CA
American journal of reproductive immunology and microbiology : AJRIM · 1985 · vol. 8(3) , pp. 84–86 · doi:10.1111/j.1600-0897.1985.tb00314.x · PMID:3895994 · W2286383015
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This study evaluated serum antiendometrial antibodies in infertile patients, finding that 85.7% of those with positive antibody tests also had endometriosis, suggesting a potential for an immunological diagnostic test.

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Abstract

Sera from 42 patients complaining of infertility were evaluated by indirect immunofluorescence for the presence of antibodies to the endometrium. The presence or absence of antibodies was matched with the findings at laparoscopy. Of the 42 patients examined for infertility, 28 (66.7%) had laparoscopic findings that corresponded to the presence or absence of endometriosis. Of 28 patients with positive antibody tests, 24 (85.7%) were found to have endometriosis. No correlation between the degree of immunofluorescence and the clinical severity of endometriosis could be determined. These findings suggest the possibility of developing a noninvasive immunological test for the presence of endometriosis.

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Condition tags

endometriosisinfertility

MeSH descriptors

Autoantibodies Endometriosis Endometrium Infertility, Female Autoantibodies Autoantibodies Autoimmune Diseases Autoimmune Diseases Autoimmune Diseases Endometriosis Endometriosis Endometriosis Endometriosis Endometrium Endometrium Female Female Fluorescent Antibody Technique Fluorescent Antibody Technique Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (17)

Cited by (50)

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