Cognate chemokine receptor 1 messenger ribonucleic acid expression in peripheral blood as a diagnostic test for endometriosis

Admir Agic, Agic A, Xu H, Hong Xu, Rehbein M, Mirka Rehbein, Monika Wölfler, Wolfler MM, Monika M Wolfler, Ebert AD, Andreas D. Ebert, Hornung D, Daniela Hornung
Fertility and sterility · 2007 · vol. 87(4) , pp. 982–984 · doi:10.1016/j.fertnstert.2006.09.012 · PMID:17261287 · W2162655380
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Researchers investigated the diagnostic potential of cognate chemokine receptor 1 messenger ribonucleic acid expression in peripheral blood for endometriosis.

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Abstract

We investigated the expression of the cognate chemokine receptor 1 (CCR1) messenger ribonucleic acid, a G-protein-coupled cognate chemokine receptor with high affinity for RANTES (Regulated upon Activation, Normal T cells Expressed and Secreted), in peripheral blood leukocytes of women with and without endometriosis, and its potential use as a diagnostic test for endometriosis. Because patients with an earlier diagnosis of this disease have a better treatment outcome and a reduced recurrence rate, CCR1 mRNA measurement in the peripheral blood of patients with suspected endometriosis might give us a new perspective in diagnosing and treating this disease earlier and better.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Leukocytes Receptors, Chemokine RNA, Messenger CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Female Humans Leukocytes Pregnancy Receptors, CCR1 Receptors, Chemokine RNA, Messenger Sensitivity and Specificity

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References (11)

Cited by (26)

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