Diagnostische Tests für Endometriosis

A. Agic, Schima Djalali, S. Dogan, C. Altgassen, K. Diedrich, Daniela Hornung
In: Der Gynäkologe · 2007 · vol. 40(7) , pp. 527–531 · doi:10.1007/s00129-007-2010-y · W22421893
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

A diagnostic test for endometriosis using peripheral blood is urgently needed due to the long diagnostic delay, with markers like CA 125 and IL-6 being investigated.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The paper addresses the diagnostic delay in endometriosis, noting that the time from initial symptoms to definitive diagnosis by laparoscopy is still about 6–7 years, and it evaluates the need for a noninvasive diagnostic test, ideally from peripheral blood. It synthesizes evidence that candidate biomarkers may include CA 125, CA 19–9, IL-6, ICAM-1, and CCR-1 mRNA, with regression models that can also incorporate clinical factors such as cycle length and number of pregnancies. It argues that earlier, less invasive diagnosis could enable easier surgery at lower disease stage, reduce recurrence, and lower costs, while explicitly stating that until such a test is established, diagnosis relies on history, gynecologic exam, ultrasound, and ultimately laparoscopy. This paper is centrally about endometriosis — it focuses on diagnostic tests, especially noninvasive blood-based markers, to shorten the diagnostic delay.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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