Biomarkers of endometriosis

Anuja Pant; Kareena Moar; Taruna Arora; Taruna K Arora; Pawan Kumar Maurya

doi:10.1016/j.cca.2023.117563

Biomarkers of endometriosis

Anuja Pant, Kareena Moar, Taruna Arora, Taruna K Arora, Pawan Kumar Maurya

Clinica chimica acta; international journal of clinical chemistry · 2023 · vol. 549 , pp. 117563 · doi:10.1016/j.cca.2023.117563 · PMID:37739024 · W4386898412

review OA: closed CC0 ⤵ 19 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper identifies and analyzes biomarkers associated with endometriosis, providing insights into its underlying biological mechanisms and potential diagnostic avenues.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Biomarkers Biomarkers Biomarkers Biomarkers Biomarkers Biomarkers Female Female Female Female Female Female Humans

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References (100)

Accurate diagnosis of endometriosis using serum microRNAs via openalex
A comparison between serum levels of interleukin-6 and CA125 in patients with endometriosis and normal women. via openalex
Advances in Imaging for Assessing Pelvic Endometriosis via openalex
Anti-inflammatory cytokines in endometriosis via openalex
Cell cycle, apoptosis, cell differentiation, and lipid metabolism gene expression in endometriotic tissue and exposure to parabens and benzophenones via openalex
Circulating MicroRNAs Identified in a Genome-Wide Serum MicroRNA Expression Analysis as Noninvasive Biomarkers for Endometriosis via openalex
Clinical Management of Endometriosis via openalex
Clinical Usefulness of Cancer Antigen (CA) 125, Human Epididymis 4, and CA72-4 Levels and Risk of Ovarian Malignancy Algorithm Values for Diagnosing Ovarian Tumors in Korean Patients With and Without Endometriosis via openalex
Comparison of #Enzian classification and revised American Society for Reproductive Medicine stages for the description of disease extent in women with deep endometriosis via openalex
Current treatments for endometriosis in South Korea: an analysis of nationwide data from 2010 to 2019 via openalex
Diagnosis and management of endometriosis: The role of the advanced practice nurse in primary care via openalex
Diagnosis of endometriosis in the 21st century via openalex
Diagnostic accuracy of Cancer Antigen 125 (CA125) for endometriosis in symptomatic women: A multi-center study via openalex
Diagnostic Accuracy of Urinary Cytokeratin 19 Fragment for Endometriosis via openalex
Distinct molecular pathways in ovarian endometrioid adenocarcinoma with concurrent endometriosis via openalex
Dysmenorrhea, Endometriosis and Chronic Pelvic Pain in Adolescents via openalex
Elevated glycodelin-A concentrations in serum and peritoneal fluid of women with ovarian endometriosis via openalex
Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report via openalex
Elevated urine histone 4 levels in women with ovarian endometriosis revealed by discovery and parallel reaction monitoring proteomics via openalex
Endometrial expression of estrogen receptor β and its splice variants in patients with and without endometriosis via openalex
Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment via openalex
Endometriosis and Infertility via openalex
Endometriosis and nuclear receptors via openalex
Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis via openalex
Endometriosis: Evaluation and Treatment. via openalex
Endometriosis: pathogenesis and treatment via openalex
Evaluation and Medical Management of Chronic Pelvic Pain via openalex
Evaluation of elevated urinary enolase I levels in patients with endometriosis via openalex
Evaluation of FAS and caspase-3 in the endometrial tissue of patients with idiopathic infertility and recurrent pregnancy loss via openalex
Evaluation of Serum Endocan Levels in Endometriosis: A case-control study. via openalex
Evaluation of Uterosacral Ligament Involvement in Deep Endometriosis by Transvaginal Ultrasonography via openalex
Exosomes derived from endometriotic stromal cells have enhanced angiogenic effects in vitro via openalex
Expression of inflammatory cytokines in serum and peritoneal fluid from patients with different stages of endometriosis via openalex
Expression of MMIF, HIF-1α and VEGF in Serum and Endometrial Tissues of Patients with Endometriosis via openalex
Follistatin-like I promotes endometriosis by increasing proinflammatory factors and promoting angiogenesis via openalex
Functional MicroRNA Involved in Endometriosis via openalex
High serum follistatin levels in women with ovarian endometriosis via openalex
Histotyping and grading of endometriosis and its association with clinico-pathological parameters via openalex
Identification of miR-34-3p as a candidate follicular phase serum marker for endometriosis: a pilot study via openalex
Identification of Susceptibility Genes for Peritoneal, Ovarian, and Deep Infiltrating Endometriosis Using a Pooled Sample-Based Genome-Wide Association Study via openalex
IGF-I stimulates ERβ and aromatase expression via IGF1R/PI3K/AKT-mediated transcriptional activation in endometriosis via openalex
Immunology of endometriosis via openalex
Impaired CRH and Urocortin Expression and Function in Eutopic Endometrium of Women with Endometriosis via openalex
Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene–α (Gro-α) from endometrioma stromal cells via openalex
Interleukin in endometriosis-associated infertility-pelvic pain: systematic review and meta-analysis via openalex
Management of endometriomas via openalex
May endocan be a new biomarker in the diagnosis of endometriosis? via openalex
Measurable serum markers of oxidative stress response in women with endometriosis via openalex
Menstruation Dysregulation and Endometriosis Development via openalex
Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium via openalex
miR 31-3p Has the Highest Expression in Cesarean Scar Endometriosis via openalex
miRNA serum testing for endometriosis: recent headway on the path to clinical utility via openalex
Molecular aspects of development and regulation of endometriosis via openalex
Molecular Mechanisms of Endometriosis Revealed Using Omics Data via openalex
New concepts on the etiology of endometriosis via openalex
New Insights in Pathogenesis of Endometriosis via openalex
Oncological markers CA-125, CA 19-9 and endometriosis via openalex
Oxidative Stress Statues in Serum and Follicular Fluid of Women with Endometriosis. via openalex
Pathogenic mechanisms in endometriosis-associated infertility via openalex
Peripheral biomarkers of endometriosis: a systematic review via openalex
Peritoneal endometriosis is an inflammatory disease via openalex
Plasma urocortin-1 as a preoperative marker of endometriosis in symptomatic women via openalex
Plasma Urocortin Levels in the Diagnosis of Ovarian Endometriosis via openalex
PPAR-γ expression in peritoneal endometriotic lesions correlates with pain experienced by patients via openalex
Quantity and quality of retrograde menstruation: a case control study via openalex
Rethinking mechanisms, diagnosis and management of endometriosis via openalex
Role of miRNAs in Normal Endometrium and in Endometrial Disorders: Comprehensive Review via openalex
Self-management strategies amongst Australian women with endometriosis: a national online survey via openalex
Serum and peritoneal evaluation of vitamin D-binding protein in women with endometriosis. via openalex
Serum and Peritoneal Fluid Levels of Vascular Endothelial Growth Factor in Women with Endometriosis via openalex
Serum anti-inflammatory cytokines for the evaluation of inflammatory status in endometriosis via openalex
Serum carcinogenic antigen (CA)-125 and CA 19-9 combining pain score in the diagnosis of pelvic endometriosis in infertile women via openalex
Serum Markers for the Noninvasive Diagnosis of Endometriosis via openalex
Targeting oxidative stress to treat endometriosis via openalex
The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing via openalex
The Endometriotic Tissue Lining the Internal Surface of Endometrioma: Hormonal, Genetic, Epigenetic Status, and Gene Expression Profile via openalex
The Origin and Pathogenesis of Endometriosis via openalex
The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights via openalex
The role of cytokeratin 19 levels in the determination of endometriosis stages via openalex
The Role of Serum Caspase 3 Levels in Prediction of Endometriosis Severity via openalex
The Search for Biomarkers in Endometriosis: a Long and Windy Road via openalex
Update on Biomarkers for the Detection of Endometriosis via openalex
Update on endometriosis pathogenesis via openalex
Urinary Biomarkers for Detection of Clinical Endometriosis or Adenomyosis via openalex
Urocortin 2 and urocortin 3 in endometriosis: evidence for a possible role in inflammatory response via openalex
Urocortin and corticotrophin-releasing hormone receptor type 2 mRNA are highly expressed in deep infiltrating endometriotic lesions via openalex
Use of dienogest in endometriosis: a narrative literature review and expert commentary via openalex
Vascular Endothelial Growth Factor Serum Levels in Women with Advanced Endometriosis via openalex
Vitamin D-Binding Protein in Pregnancy and Reproductive Health via openalex
World Endometriosis Society consensus on the classification of endometriosis via openalex
W2938892895 via openalex
W2754055756 via openalex
W2520625765 via openalex
W1543707496 via openalex
W2276274613 via openalex
W3133274832 via openalex
W3134885188 via openalex
W2170070360 via openalex
W2165796043 via openalex
W3156807179 via openalex

Cited by (19)

Source provenance

europepmc: last seen: 2026-06-04T01:30:01.192114+00:00
openalex: last seen: 2026-06-04T00:00:01.174412+00:00
pubmed: last seen: 2026-05-29T00:33:19.715729+00:00

License: CC0 · commercial use OK

[1] Accurate diagnosis of endometriosis using serum microRNAs via openalex

[2] A comparison between serum levels of interleukin-6 and CA125 in patients with endometriosis and normal women. via openalex

[3] Advances in Imaging for Assessing Pelvic Endometriosis via openalex

[4] Anti-inflammatory cytokines in endometriosis via openalex

[5] Cell cycle, apoptosis, cell differentiation, and lipid metabolism gene expression in endometriotic tissue and exposure to parabens and benzophenones via openalex

[6] Circulating MicroRNAs Identified in a Genome-Wide Serum MicroRNA Expression Analysis as Noninvasive Biomarkers for Endometriosis via openalex

[7] Clinical Management of Endometriosis via openalex

[8] Clinical Usefulness of Cancer Antigen (CA) 125, Human Epididymis 4, and CA72-4 Levels and Risk of Ovarian Malignancy Algorithm Values for Diagnosing Ovarian Tumors in Korean Patients With and Without Endometriosis via openalex

[9] Comparison of #Enzian classification and revised American Society for Reproductive Medicine stages for the description of disease extent in women with deep endometriosis via openalex

[10] Current treatments for endometriosis in South Korea: an analysis of nationwide data from 2010 to 2019 via openalex

[11] Diagnosis and management of endometriosis: The role of the advanced practice nurse in primary care via openalex

[12] Diagnosis of endometriosis in the 21st century via openalex

[13] Diagnostic accuracy of Cancer Antigen 125 (CA125) for endometriosis in symptomatic women: A multi-center study via openalex

[14] Diagnostic Accuracy of Urinary Cytokeratin 19 Fragment for Endometriosis via openalex

[15] Distinct molecular pathways in ovarian endometrioid adenocarcinoma with concurrent endometriosis via openalex

[16] Dysmenorrhea, Endometriosis and Chronic Pelvic Pain in Adolescents via openalex

[17] Elevated glycodelin-A concentrations in serum and peritoneal fluid of women with ovarian endometriosis via openalex

[18] Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report via openalex

[19] Elevated urine histone 4 levels in women with ovarian endometriosis revealed by discovery and parallel reaction monitoring proteomics via openalex

[20] Endometrial expression of estrogen receptor β and its splice variants in patients with and without endometriosis via openalex

[21] Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment via openalex

[22] Endometriosis and Infertility via openalex

[23] Endometriosis and nuclear receptors via openalex

[24] Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis via openalex

[25] Endometriosis: Evaluation and Treatment. via openalex

[26] Endometriosis: pathogenesis and treatment via openalex

[27] Evaluation and Medical Management of Chronic Pelvic Pain via openalex

[28] Evaluation of elevated urinary enolase I levels in patients with endometriosis via openalex

[29] Evaluation of FAS and caspase-3 in the endometrial tissue of patients with idiopathic infertility and recurrent pregnancy loss via openalex

[30] Evaluation of Serum Endocan Levels in Endometriosis: A case-control study. via openalex

[31] Evaluation of Uterosacral Ligament Involvement in Deep Endometriosis by Transvaginal Ultrasonography via openalex

[32] Exosomes derived from endometriotic stromal cells have enhanced angiogenic effects in vitro via openalex

[33] Expression of inflammatory cytokines in serum and peritoneal fluid from patients with different stages of endometriosis via openalex

[34] Expression of MMIF, HIF-1α and VEGF in Serum and Endometrial Tissues of Patients with Endometriosis via openalex

[35] Follistatin-like I promotes endometriosis by increasing proinflammatory factors and promoting angiogenesis via openalex

[36] Functional MicroRNA Involved in Endometriosis via openalex

[37] High serum follistatin levels in women with ovarian endometriosis via openalex

[38] Histotyping and grading of endometriosis and its association with clinico-pathological parameters via openalex

[39] Identification of miR-34-3p as a candidate follicular phase serum marker for endometriosis: a pilot study via openalex

[40] Identification of Susceptibility Genes for Peritoneal, Ovarian, and Deep Infiltrating Endometriosis Using a Pooled Sample-Based Genome-Wide Association Study via openalex

[41] IGF-I stimulates ERβ and aromatase expression via IGF1R/PI3K/AKT-mediated transcriptional activation in endometriosis via openalex

[42] Immunology of endometriosis via openalex

[43] Impaired CRH and Urocortin Expression and Function in Eutopic Endometrium of Women with Endometriosis via openalex

[44] Interleukin-17A is present in neutrophils in endometrioma and stimulates the secretion of growth-regulated oncogene–α (Gro-α) from endometrioma stromal cells via openalex

[45] Interleukin in endometriosis-associated infertility-pelvic pain: systematic review and meta-analysis via openalex

[46] Management of endometriomas via openalex

[47] May endocan be a new biomarker in the diagnosis of endometriosis? via openalex

[48] Measurable serum markers of oxidative stress response in women with endometriosis via openalex

[49] Menstruation Dysregulation and Endometriosis Development via openalex

[50] Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium via openalex

[51] miR 31-3p Has the Highest Expression in Cesarean Scar Endometriosis via openalex

[52] miRNA serum testing for endometriosis: recent headway on the path to clinical utility via openalex

[53] Molecular aspects of development and regulation of endometriosis via openalex

[54] Molecular Mechanisms of Endometriosis Revealed Using Omics Data via openalex

[55] New concepts on the etiology of endometriosis via openalex

[56] New Insights in Pathogenesis of Endometriosis via openalex

[57] Oncological markers CA-125, CA 19-9 and endometriosis via openalex

[58] Oxidative Stress Statues in Serum and Follicular Fluid of Women with Endometriosis. via openalex

[59] Pathogenic mechanisms in endometriosis-associated infertility via openalex

[60] Peripheral biomarkers of endometriosis: a systematic review via openalex

[61] Peritoneal endometriosis is an inflammatory disease via openalex

[62] Plasma urocortin-1 as a preoperative marker of endometriosis in symptomatic women via openalex

[63] Plasma Urocortin Levels in the Diagnosis of Ovarian Endometriosis via openalex

[64] PPAR-γ expression in peritoneal endometriotic lesions correlates with pain experienced by patients via openalex

[65] Quantity and quality of retrograde menstruation: a case control study via openalex

[66] Rethinking mechanisms, diagnosis and management of endometriosis via openalex

[67] Role of miRNAs in Normal Endometrium and in Endometrial Disorders: Comprehensive Review via openalex

[68] Self-management strategies amongst Australian women with endometriosis: a national online survey via openalex

[69] Serum and peritoneal evaluation of vitamin D-binding protein in women with endometriosis. via openalex

[70] Serum and Peritoneal Fluid Levels of Vascular Endothelial Growth Factor in Women with Endometriosis via openalex

[71] Serum anti-inflammatory cytokines for the evaluation of inflammatory status in endometriosis via openalex

[72] Serum carcinogenic antigen (CA)-125 and CA 19-9 combining pain score in the diagnosis of pelvic endometriosis in infertile women via openalex

[73] Serum Markers for the Noninvasive Diagnosis of Endometriosis via openalex

[74] Targeting oxidative stress to treat endometriosis via openalex

[75] The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing via openalex

[76] The Endometriotic Tissue Lining the Internal Surface of Endometrioma: Hormonal, Genetic, Epigenetic Status, and Gene Expression Profile via openalex

[77] The Origin and Pathogenesis of Endometriosis via openalex

[78] The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights via openalex

[79] The role of cytokeratin 19 levels in the determination of endometriosis stages via openalex

[80] The Role of Serum Caspase 3 Levels in Prediction of Endometriosis Severity via openalex

[81] The Search for Biomarkers in Endometriosis: a Long and Windy Road via openalex

[82] Update on Biomarkers for the Detection of Endometriosis via openalex

[83] Update on endometriosis pathogenesis via openalex

[84] Urinary Biomarkers for Detection of Clinical Endometriosis or Adenomyosis via openalex

[85] Urocortin 2 and urocortin 3 in endometriosis: evidence for a possible role in inflammatory response via openalex

[86] Urocortin and corticotrophin-releasing hormone receptor type 2 mRNA are highly expressed in deep infiltrating endometriotic lesions via openalex

[87] Use of dienogest in endometriosis: a narrative literature review and expert commentary via openalex

[88] Vascular Endothelial Growth Factor Serum Levels in Women with Advanced Endometriosis via openalex

[89] Vitamin D-Binding Protein in Pregnancy and Reproductive Health via openalex

[90] World Endometriosis Society consensus on the classification of endometriosis via openalex

[91] W2938892895 via openalex

[92] W2754055756 via openalex

[93] W2520625765 via openalex

[94] W1543707496 via openalex

[95] W2276274613 via openalex

[96] W3133274832 via openalex

[97] W3134885188 via openalex

[98] W2170070360 via openalex

[99] W2165796043 via openalex

[100] W3156807179 via openalex