Serum Markers for the Noninvasive Diagnosis of Endometriosis
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Researchers investigated serum markers for noninvasively diagnosing endometriosis, finding that a panel of biomarkers shows more promise than single markers due to diagnostic challenges with current methods.
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Abstract
Endometriosis is a disease that affects millions of women worldwide and its diagnosis is still challenging. Medical history, symptoms together with imaging data may address the correct diagnosis, but the gold standard remains laparoscopic assessment with histological confirmation. The development of serum markers as diagnostic tools for endometriosis may allow a prompt and noninvasive diagnosis. Several serum biomarkers have been investigated over the years, but none of these have shown a clinical utility and nowadays the more realistic diagnostic biomarker consists in a panel of biomarkers. The recent introduction of new technologies such as genomics and proteomics may represent the future perspective of endometriosis diagnosis.
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Cited by (21)
- Association between serum carotenoids and risk of endometriosis evidence from NHANES data 2025
- The Known, the Unknown and the Future of the Pathophysiology of Endometriosis 2024
- Endometriosis-Associated Infertility: The Role of Biomarkers of Apoptosis and Proliferation in Early Noninvasive Diagnosis 2024
- Enhancing endometrioma management: Diagnostic biomarkers and predictive outcomes in Ruptured vs. Non-Ruptured cases 2024
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- Biomarkers of endometriosis 2023
- Multicenter evaluation of blood‐based biomarkers for the detection of endometriosis and adenomyosis: A prospective non‐interventional study 2023
- Significance of metabolomic disorders in infertility and miscarriage in patients with endometriosis 2022
- Novel methods in diagnosis of endometriosis in future 2022
- Non-invasive diagnosis of endometriosis: Immunologic and genetic markers 2022
- Novel Diagnostic Markers for Endometriosis 2021
- Metabolomics in endometriosis: challenges and perspectives for future studies 2021
- Application of serum markers in diagnosis and staging of ovarian endometriosis 2021
- The Potential of Non-Invasive Biomarkers for Early Diagnosis of Asymptomatic Patients with Endometriosis 2021
- The Link Between Stress and Endometriosis: from Animal Models to the Clinical Scenario 2020
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