Current treatments for endometriosis in South Korea: an analysis of nationwide data from 2010 to 2019

Han Kyul Kim, Han‐Kyul Kim, Eun‐San Kim, Eun-San Kim, Kyoung Sun Park, Yoon Jae Lee, In‐Hyuk Ha, In-Hyuk Ha
Scientific reports · 2023 · vol. 13(1) , pp. 9573 · doi:10.1038/s41598-023-36291-1 · PMID:37311821 · PMC10264383 · W4380538003
article OA: gold CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study analyzed Korean healthcare data from 2010-2019, finding that conservative medical treatment, particularly dienogest, has gradually replaced surgery for endometriosis patients.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This retrospective analysis used Korean Health Insurance Review & Assessment Service–National Patient Sample data from 2010–2019 to describe treatment patterns and healthcare costs among 7,530 patients with endometriosis as the primary diagnosis, including outpatient use, admissions, surgery (including laparoscopy), and medication prescriptions. Across the study period, surgery utilization modestly declined, dienogest prescriptions increased sharply after national insurance coverage in 2013, and gonadotropin-releasing hormone analogues decreased, while total and outpatient costs per person showed no significant overall change. The authors defined endometriosis using specific diagnostic codes and did not exclude patients with comorbidities, including adenomyosis, and they treated analyses as descriptive with costs reflecting claims-based utilization. This paper is centrally about endometriosis — it characterizes national-level trends in medical and surgical treatments for endometriosis in South Korea.

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Abstract

While a wide range of treatments, including medical therapies and surgery, are used to manage endometriosis, the characteristics and treatment status of patients who received these treatments have not been investigated in Korea. This study analyzed the Korean Health Insurance Review & Assessment Service-National Patient Sample (HIRA-NPS) data from 2010 to 2019 with 7530 patients diagnosed with endometriosis. Annual trends in the types of visit and surgery, medication prescriptions and associated costs were investigated. The analysis showed that surgery slightly decreased among the types of utilized healthcare services (2010: 16.3, 2019: 12.7), dienogest prescription rapidly increased due to national health insurance coverage from 2013 (2013: 12.1, 2019: 36.0), and the use of gonadotrophin-releasing hormone analogues decreased (2010: 33.6, 2019: 16.4). There was no significant change in total and outpatient costs per person over time. Regarding endometriosis treatment, conservative treatment mainly based on prescribed medications has been gradually replacing surgery. Particularly, the listing of dienogest for national health insurance coverage might have affected the trend. However, there were no significant changes in terms of total and medication costs per person.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Conservative Treatment Conservative Treatment Conservative Treatment Conservative Treatment Conservative Treatment Conservative Treatment Conservative Treatment

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