The Estimated Prevalence and Incidence of Endometriosis With the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC): A National Population-Based Study

Hyun-Kyung Kim, Minkyoung Lee, Hye‐Jin Hwang, Hyejin Hwang, Youn‐Jee Chung, Youn-Jee Chung, Hyun‐Hee Cho, Hyun-Hee Cho, Hyonjee Yoon, Mi‐Ra Kim, Mira Kim, Kyunghee Chae, Kyung-Hee Chae, Chai Young Jung, Sukil Kim, Mee‐Ran Kim, Mee-Ran Kim
Journal of epidemiology · 2020 · vol. 31(12) , pp. 593–600 · doi:10.2188/jea.je20200002 · PMID:32863371 · PMC8593577 · W3082236987
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study estimated endometriosis prevalence and incidence in Korea using national health insurance claims, finding lower rates than previous high-risk studies but a significant increase in younger age groups.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This paper estimated the prevalence and incidence of endometriosis in Korea using a retrospective cohort design based on Korean National Health Insurance Service-National Sample Cohort claims data covering about 1 million people from 2002 to 2013, focusing on patients aged 15–54 and calculating estimates by time and age groups. The age-adjusted prevalence increased from 2.12 per 1,000 persons in 2002 to 3.56 per 1,000 persons in 2013, while the average adjusted incidence showed no statistically significant overall increase. In contrast, age-specific incidence increased significantly among younger groups (15–19 and 20–24 years) from 2003 to 2013, but decreased in midlife groups (40–44 and 45–49 years) over the same period. The paper relates to endometriosis by providing national population-based estimates of its prevalence and incidence in Korean women, showing rising diagnosis in younger age groups. This paper is centrally about endometriosis — it estimates its national prevalence and incidence in Korea using insurance claims data.

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Abstract

BACKGROUND: The incidence and prevalence of endometriosis remain unclear due to diagnostic difficulties. Especially, there has been little information regarding the population-based epidemiology of endometriosis. The purpose of this study is to estimate the prevalence and incidence of endometriosis in Korea based on the health insurance claims data. METHODS: This study is a retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort, which correspond to approximately 1 million Korean populations from 2002 to 2013. Patients aged 15-54 years were selected, and the prevalence and incidence of endometriosis were estimated by time and age groups. RESULTS: = 0.83 and 0.89, P < 0.001). CONCLUSION: The prevalence and incidence of endometriosis in Korean women were lower than that of previous reports in high-risk population studies. Furthermore, we found a significant increase in the diagnosis of endometriosis in younger age groups.
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Abstract

Background: The incidence and prevalence of endometriosis remain unclear due to diagnostic difficulties. Especially, there has been little information regarding the population-based epidemiology of endometriosis. The purpose of this study is to estimate the prevalence and incidence of endometriosis in Korea based on the health insurance claims data.

Methods

This study is a retrospective cohort study using the Korean National Health Insurance Service-National Sample Cohort, which correspond to approximately 1 million Korean populations from 2002 to 2013. Patients aged 15–54 years were selected, and the prevalence and incidence of endometriosis were estimated by time and age groups.

Results

The age-adjusted prevalence rate of endometriosis also increased from 2.12 per 1,000 persons (95% confidence interval [CI], 2.01–2.24) in 2002 to 3.56 per 1,000 persons (95% CI, 3.40–3.71) in 2013. The average adjusted incidence showed no statistically significant increase. However, the age-specific incidence of the 15–19 and 20–24 years age groups increased significantly from 0.24 and 1.29 per 1,000 persons in 2003 to 2.73 and 2.71 per 1,000 persons in 2013 (R2 = 0.93 and 0.77, P < 0.001), while the incidence rate of the age group 40–44 and 45–49 years decreased from 2.36 and 1.72 per 1,000 persons in 2003 to 0.81 and 0.27 per 1,000 persons in 2013 (R2 = 0.83 and 0.89, P < 0.001).

Conclusion

The prevalence and incidence of endometriosis in Korean women were lower than that of previous reports in high-risk population studies. Furthermore, we found a significant increase in the diagnosis of endometriosis in younger age groups. © 2020 Hyunkyung Kim et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Favorites & Alerts Recently viewed articles

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Cohort Studies Female Humans Incidence National Health Programs Prevalence Republic of Korea Republic of Korea Retrospective Studies

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