Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription

Anitha S Nair, A.S. Nair, Hareesh B Nair, Richard S Lucidi, R.S. Lucidi, Alyson J Kirchner, Robert S Schenken, Rajeshwar R. Tekmal, Rajeshwar Rao Tekmal, Craig A Witz
Fertility and sterility · 2008 · vol. 90(4) , pp. 1487–1495 · doi:10.1016/j.fertnstert.2007.09.047 · PMID:18163995 · W1990329963
article OA: closed CC0 ⤵ 45 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Co-culturing mesothelial and endometrial cells in vitro models early endometriotic lesions by increasing endometrial invasion and altering gene transcription in both cell types.

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MeSH descriptors

Cell Movement Endometrium Epithelium Models, Biological Transcription, Genetic Adult Cell Adhesion Cells, Cultured Coculture Techniques Endometrium Epithelium Female Gene Expression Humans

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License: CC0 · commercial use OK