Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells

Sabitha Aligeti; Aligeti S; Kirma NB; Nameer B Kirma; Peter A Binkley; Peter Binkley; Binkley PA; Schenken RS; Robert S Schenken; Tekmal RR; Rajeshwar Rao Tekmal; Rajeshwar R. Tekmal

doi:10.1016/j.fertnstert.2011.03.026

Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells

Sabitha Aligeti, Aligeti S, Kirma NB, Nameer B Kirma, Peter A Binkley, Peter Binkley, Binkley PA, Schenken RS, Robert S Schenken, Tekmal RR, Rajeshwar Rao Tekmal, Rajeshwar R. Tekmal

Fertility and sterility · 2011 · vol. 95(8) , pp. 2464–2466 · doi:10.1016/j.fertnstert.2011.03.026 · PMID:21481374 · PMC3124585 · W2057354912

article OA: bronze CC0 ⤵ 6 in-corpus citations

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Colony-stimulating factor-1 directly promotes the proliferation and invasiveness of endometrial epithelial cells.

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Abstract

Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion formation. We have shown that CSF-1, in an autocrine fashion, has a direct effect on endometrial epithelial cell proliferation and attachment to peritoneal mesothelial cells, early steps in endometriosis lesion formation on the peritoneum.

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Condition tags

endometriosis

MeSH descriptors

Cell Movement Cell Proliferation Endometriosis Endometrium Epithelial Cells Macrophage Colony-Stimulating Factor Analysis of Variance Autocrine Communication Cell Adhesion Cell Line Coculture Techniques Endometriosis Endometriosis Endometrium Endometrium Epithelial Cells Epithelial Cells Female Humans Macrophage Colony-Stimulating Factor

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References (25)

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Cell of the mucous membrane of the female genital tract in culture: A comparative study with regard to the histogenesis of endometriosis via openalex
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[1] A potential role for colony-stimulating factor 1 in the genesis of the early endometriotic lesion via openalex

[2] Cell of the mucous membrane of the female genital tract in culture: A comparative study with regard to the histogenesis of endometriosis via openalex

[3] Culture of menstrual endometrium with peritoneal explants and mesothelial monolayers confirms attachment to intact mesothelial cells via openalex

[4] Effects of peritoneal fluid from endometriosis patients on the release of monocyte-specific chemokines by leukocytes via openalex

[5] Endometriosis: its association with retrograde menstruation, dysmenorrhoea and tubal pathology via openalex

[6] Endometriosis: Its association with retrograde menstruation, dysmenorrhoea and tubal pathology via openalex

[7] Experimental endometriosis in the human via openalex

[8] EXTERNAL ENDOMETRIOSIS-THE SCOURGE OF THE PRIVATE PATIENT via openalex

[9] Extracellular matrix metalloproteinase inducer expression in the baboon endometrium: menstrual cycle and endometriosis via openalex

[10] Identification of the M‐CSF Receptor in Endometriosis by Immunohistochemistry and RT‐PCR via openalex

[11] Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription via openalex

[12] Peritoneal fluid and plasma levels of human macrophage colony- stimulating factor in relation to peritoneal fluid macrophage content via openalex

[13] Regulatory T cells and other leukocytes in the pathogenesis of endometriosis via openalex

[14] Retrograde menstruation in healthy women and in patients with endometriosis. via openalex

[15] Short-term culture of peritoneum explants confirms attachment of endometrium to intact peritoneal mesothelium via openalex

[16] W6628680024 via openalex

[17] W84817672 via openalex

[18] W1964846497 via openalex

[19] W1987520465 via openalex

[20] W1993032507 via openalex

[21] W2017967258 via openalex

[22] W2031336219 via openalex

[23] W2064556766 via openalex

[24] W2091982547 via openalex

[25] W2115140869 via openalex