Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons

D'Hooghe TM, Thomas D'Hooghe, Thomas D’Hooghe, Thomas M D'Hooghe, Debrock S, Sophie Debrock
Human Reproduction Update · 2002 · vol. 8(1) , pp. 84–88 · doi:10.1093/humupd/8.1.84 · PMID:11866244 · W2143537649
Review OA: bronze CC0 ⤵ 185 in-corpus citations
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This review critically assesses the evidence in women and baboons for retrograde menstruation as a key factor in endometriosis pathogenesis, highlighting the need for further understanding of menstrual events in the peritoneal environment.

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Abstract

The aim of this review was to assess critically the importance of the frequency, quantity and quality of retrograde menstruation and its relationship to peritoneal inflammation. The basis was the current evidence in women and in baboons supporting the Sampson hypothesis that retrograde menstruation is a key factor in the pathogenesis of endometriosis. It is not proven that retrograde menstruation is a universal phenomenon occurring similarly in women with and without endometriosis. A more thorough understanding of the physiological, cytological and immunological events in peritoneal fluid, peritoneum, endometrium and uterus during menstruation in women with and without endometriosis is critical in order to understand the pathogenesis of this enigmatic disease.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Menstruation Disturbances Peritonitis Animals Animals Disease Models, Animal Disease Models, Animal Endometriosis Endometriosis Female Female Humans Humans Menstruation Disturbances Menstruation Disturbances Menstruation Disturbances Papio Papio Peritonitis Peritonitis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (45)

Cited by (50)

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