Endometriosis: current challenges and treatment prospects
This review examines endometriosis pathogenesis, risk factors, symptoms, diagnosis, and treatment, emphasizing early detection and integrated management for improved patient quality of life.
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This paper reviews the epidemiology, symptom profile, risk factors, and treatment prospects of endometriosis, summarizing prevalence estimates across different populations (e.g., infertile women, women undergoing laparoscopy for chronic pelvic pain, and general population surveys) and noting that reported prevalence varies widely by setting. It outlines common symptoms—chronic pelvic pain, dysmenorrhea, dyspareunia, and menstrual-linked gastrointestinal and urinary symptoms—and emphasizes that endometriosis can also present as infertility without other complaints. The paper lists risk factors including early menarche, short menstrual cycles, low BMI, alcohol intake, and certain dietary patterns, such as higher red meat consumption associated with increased risk, while reporting no association for poultry, fish, shellfish, and eggs in the cited study, and it does not provide a single primary methodological limitation beyond the variability inherent in the prevalence estimates. This paper is centrally about endometriosis — it focuses on current challenges and treatment prospects via a synthesis of prevalence, symptoms, and risk factors.
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References (57)
- A systematic review on the prevalence of endometriosis in women via openalex
- Biomarkers in endometriosis: challenges and opportunities via openalex
- Clinical Management of Endometriosis via openalex
- Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF‐κB signaling pathway via openalex
- Current and Emerging Therapeutics for the Management of Endometriosis via openalex
- Diagnosis and management of endometriosis via openalex
- Endometriosis via openalex
- Endometriosis via openalex
- Endometriosis: A Disease with Few Direct Treatment Options via openalex
- Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment via openalex
- Endometriosis and dysbiosis: State of art via openalex
- Endometriosis and infertility: a committee opinion via openalex
- Endometriosis: A review of recent evidence and guidelines via openalex
- Endometriosis‐associated infertility: aspects of pathophysiological mechanisms and treatment options via openalex
- Endometriosis-associated infertility: From pathophysiology to tailored treatment via openalex
- Endometriosis in MRKH cases as a proof for the coelomic metaplasia hypothesis? via openalex
- Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons via openalex
- Histological assessment of impact of ovarian endometrioma and laparoscopic cystectomy on ovarian reserve via openalex
- Laparoscopic Surgery for Severe Rectovaginal Endometriosis Compromising the Bowel: A Prospective Cohort Study via openalex
- Letrozole combined with oral contraceptives versus oral contraceptives alone in the treatment of endometriosis-related pain symptoms: a pilot study via openalex
- Molecular detection of microbial colonization in cervical mucus of women with and without endometriosis via openalex
- New Insights in Pathogenesis of Endometriosis via openalex
- New Understanding of Diagnosis, Treatment and Prevention of Endometriosis via openalex
- Novel pharmacological therapies for the treatment of endometriosis via openalex
- Pathogenesis Based Diagnosis and Treatment of Endometriosis via openalex
- Pathogenesis of endometriosis: Look no further than John Sampson via openalex
- Pathogenesis of Endometriosis: New Insights into Prospective Therapies via openalex
- Pathogenesis of endometriosis: the genetic/epigenetic theory via openalex
- Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? via openalex
- Selected food intake and risk of endometriosis via openalex
- SnapShot: Endometriosis via openalex
- Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink? via openalex
- Targeting oxidative stress to treat endometriosis via openalex
- The bidirectional relationship between endometriosis and microbiome via openalex
- The Effects and Possible Mechanisms of Puerarin to Treat Endometriosis Model Rats via openalex
- The Main Theories on the Pathogenesis of Endometriosis via openalex
- The Origin and Pathogenesis of Endometriosis via openalex
- The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain via openalex
- The Role of the Lymphatic System in Endometriosis: A Comprehensive Review of the Literature1 via openalex
- Treatment of endometriosis: a review with comparison of 8 guidelines via openalex
- Vascular endothelial growth factor A and C gene expression in endometriosis via openalex
- W2119709673 via openalex
- W2101766472 via openalex
- W2097972396 via openalex
- W4387345293 via openalex
- W4403161751 via openalex
- W3194419458 via openalex
- W4406432700 via openalex
- W3202177173 via openalex
- W3165294846 via openalex
- W3119380823 via openalex
- W3118519121 via openalex
- W4214754424 via openalex
- W2944310141 via openalex
- W2810983458 via openalex
- W2415019805 via openalex
- W2132577372 via openalex
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