Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review)

Alfonso Baldi, Mara Campioni, Pietro G Signorile
Oncology reports · 2008 · vol. 19(4) , pp. 843–6 · doi:10.3892/or.19.4.843 · PMID:18357365 · W1966199527
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review summarizes recent advancements in the pathogenesis, diagnosis, and therapy of endometriosis, a common reproductive disease affecting 7-10% of women, and analyzes its association with cancer risk.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

This 2008 review by Baldi and colleagues summarizes the state of knowledge on endometriosis by addressing recent advances in its pathogenesis, diagnosis, and therapy, noting that the underlying disease mechanisms remain incompletely understood and existing treatments are described as unsatisfactory. The paper frames endometriosis as a painful reproductive and immunological condition affecting about 7–10% of women worldwide and synthesizes epidemiological and functional studies to analyze cancer risk in women with endometriosis. It does not present new experimental results but is limited by the scope and interpretation inherent to a narrative review of available literature. This paper is centrally about endometriosis — it reviews endometriosis pathogenesis, diagnosis, therapy, and its association with cancer.

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Abstract

Endometriosis is a painful reproductive and immunological disease afflicting about 7-10% of women worldwide. It is one of the most frequent benign gynaecological diseases; however, little is known about the pathogenetic processes leading to the development and maintenance of this disease and the currently available therapeutic strategies are unsatisfactory. The goal of this article is to review the most recent advancements in the pathogenesis, diagnosis and therapy of this disease. The risk for cancer among women with endometriosis will be analyzed in light of the most recent epidemiological and functional studies focused on this disease.
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Print ISSN: 1021-335X Online ISSN: 1791-2431 International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease. International Journal of Oncology is an international journal devoted to oncology research and cancer treatment. Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery. Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine. Oncology Letters is an international journal devoted to Experimental and Clinical Oncology. Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology. International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis. Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology. Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition. Publishes open-access research on using epigenetics to advance understanding and treatment of human disease. An International Open Access Journal Devoted to General Medicine. Review - Authors: - Pages: 843-846|Published online on: April 1, 2008https://doi.org/10.3892/or.19.4.843 - Expand metrics + Endometriosis is a painful reproductive and immunological disease afflicting about 7-10% of women worldwide. It is one of the most frequent benign gynaecological diseases; however, little is known about the pathogenetic processes leading to the development and maintenance of this disease and the currently available therapeutic strategies are unsatisfactory. The goal of this article is to review the most recent advancements in the pathogenesis, diagnosis and therapy of this disease. The risk for cancer among women with endometriosis will be analyzed in light of the most recent epidemiological and functional studies focused on this disease. Copy and paste a formatted citation Spandidos Publications style Baldi A, Campioni M and Signorile PG: Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review). Oncol Rep 19: 843-846, 2008. APA Baldi, A., Campioni, M., & Signorile, P.G. (2008). Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review). Oncology Reports, 19, 843-846. https://doi.org/10.3892/or.19.4.843 MLA Baldi, A., Campioni, M., Signorile, P. G."Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review)". Oncology Reports 19.4 (2008): 843-846. Chicago Baldi, A., Campioni, M., Signorile, P. G."Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review)". Oncology Reports 19, no. 4 (2008): 843-846. https://doi.org/10.3892/or.19.4.843

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Neoplasms Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Neoplasms Risk Factors

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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