Endometriosis and risk of ovarian cancer: what do we know?

Purpose Despite long and intensive research, endometriosis remains one of the leading causes of morbidity among premenopausal women. The majority of endometriosis-related ovarian carcinomas occur in the presence of atypical ovarian endometriosis. Nevertheless, despite the increased incidence of ovarian cancer in patients with endometriosis, our knowledge of the risk factors and mechanisms is still incomplete.

Narrative overview, synthesizing the recent findings of literature retrieved from databases.

Herein, we reviewed and summarized the most recent knowledge regarding endometriosis and ovarian cancer.

The evidence showing that patients with endometriosis have a higher risk of developing ovarian cancer is compelling. However, the question of how much higher the absolute risk is, is not fully clear. Similar content being viewed by others

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Corresponding author Ethics declarations Conflict of interest The authors declare that they have no conflict of interests. Informed consent Not relevant for this study. Ethical approval Not relevant for this study. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Králíčková, M., Laganà, A.S., Ghezzi, F. et al. Endometriosis and risk of ovarian cancer: what do we know?. Arch Gynecol Obstet 301, 1–10 (2020). https://doi.org/10.1007/s00404-019-05358-8 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00404-019-05358-8