Endometriosis and risk of ovarian cancer: what do we know?

Milena Králíčková, Antonio Simone Laganà, Fabio Ghezzi, Václav Větvička
Archives of gynecology and obstetrics · 2019 · vol. 301(1) , pp. 1–10 · doi:10.1007/s00404-019-05358-8 · PMID:31745637 · W2991409036
review OA: closed CC0 ⤵ 60 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This paper reviews and summarizes recent findings on the compelling evidence linking endometriosis to an increased risk of ovarian cancer, though the exact absolute risk remains unclear.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper is a narrative overview that synthesizes recent literature on endometriosis and the risk of ovarian cancer, focusing on epidemiologic evidence and mechanistic links, including the observation that most endometriosis-related ovarian carcinomas arise in the setting of atypical ovarian endometriosis. Across reviewed studies, the authors conclude that the association between endometriosis and a higher ovarian cancer risk is compelling, but they note that the absolute risk increase remains unclear. A key limitation acknowledged in the framing is that the work is a narrative (not systematic) review, so the comprehensiveness and effect quantification of included evidence are not assured. This paper is centrally about endometriosis — it reviews evidence on endometriosis as a risk factor for ovarian cancer and highlights uncertainty about the magnitude of absolute risk.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Ovarian Neoplasms Adult Endometriosis Endometriosis Female Humans Ovarian Neoplasms Ovarian Neoplasms Retrospective Studies Risk Factors

Citation neighborhood

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References (94)

Cited by (50)

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License: CC0 · commercial use OK