Immunological Aspects of Endometriosis: An Update
review
OA: closed
CC0
⤵ 62 in-corpus citations
AI-generated summary
This review examines the intricate interplay between the female immune system and the initiation, progression, infertility, and cancer associations of endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
PROBLEM: Endometriosis is a very complex disease that profoundly affects the quality of life of many women. METHOD OF STUDY: A review of the relationships between the female immune system and the occurrence and development of endometriosis. RESULTS: Function and dysfunction of the female immune system plays important roles in the initiation and progression of the disease and its relation to infertility and cancer. CONCLUSIONS: Owing to obvious associations between endometriosis and the immune system, future treatment strategies might be based on immunological concepts and methods.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (45)
- Advances in the genetics of endometriosis via openalex
- Anti-TNF-α treatment for pelvic pain associated with endometriosis via openalex
- A Possible Mechanism of Autoimmune‐Mediated infertility in Women with Endometriosis via openalex
- Autoimmunity in Endometriosis: Relevance to Infertility via openalex
- Different types of extragenital endometriosis: A review via openalex
- Endometriosis via openalex
- Endometriosis via openalex
- Endometriosis and infertility: pathophysiology and management via openalex
- Endometriosis and the risk of cancer with special emphasis on ovarian cancer via openalex
- Endometriosis: cost estimates and methodological perspective via openalex
- Endometriosis: in search of optimal treatment. via openalex
- Endometriosis, recurrent miscarriage and implantation failure: is there an immunological link? via openalex
- Endometriotic disease: the role of peritoneal fluid via openalex
- Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis via openalex
- High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis via openalex
- <i>ARID1A</i> Mutations in Endometriosis-Associated Ovarian Carcinomas via openalex
- <i>Endometriosis and Tissue Factor</i> via openalex
- Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis via openalex
- Lymphocytes in Endometriosis via openalex
- Metastatic or Embolic Endometriosis, due to the Menstrual Dissemination of Endometrial Tissue into the Venous Circulation. via openalex
- Molecular Pathogenesis of Endometriosis; Toll-Like Receptor-4 A896G (D299G) Polymorphism: A Novel Explanation via openalex
- New insights into the pathophysiology of endometriosis: from chronic inflammation to danger signal via openalex
- Nuclear Factor-κB (NF-κB): An Unsuspected Major Culprit in the Pathogenesis of Endometriosis That Is Still at Large? via openalex
- ORIGINAL ARTICLE: Serum Anti‐endometrial Antibodies in Infertile Women – Potential Risk Factor for Implantation Failure via openalex
- Ovarian cancer in endometriosis: molecular biology, pathology, and clinical management via openalex
- Pathogenesis of endometriosis: The role of defective ‘immunosurveillance’ via openalex
- Peritoneal Cellular Immunity and Endometriosis via openalex
- Potential involvement of the immune system in the development of endometriosis via openalex
- Regulatory T cells and other leukocytes in the pathogenesis of endometriosis via openalex
- Risk of developing ovarian cancer among women with ovarian endometrioma: a cohort study in Shizuoka, Japan via openalex
- Role of Natural Killer Cell Activity in the Pathogenesis of Endometriosis via openalex
- The co-occurrence of endometriosis with multiple sclerosis, systemic lupus erythematosus and Sjogren syndrome via openalex
- The role of nuclear factor-kappa-B p50 subunit in the development of endometriosis via openalex
- The search for genes contributing to endometriosis risk via openalex
- The use of biochemical markers in the diagnosis of pelvic endometriosis via openalex
- 'Waiting for Godot': a commonsense approach to the medical treatment of endometriosis via openalex
- W2127749649 via openalex
- W2067201007 via openalex
- W2283760758 via openalex
- W2411065761 via openalex
- W4214726381 via openalex
- W2102675401 via openalex
- W6604541379 via openalex
- W2093626831 via openalex
- W6809607798 via openalex
Cited by (50)
- Intestinal endometriosis: Current aspects of pathogenesis, clinical picture, and differential diagnosis (a review of foreign literature) 2026
- Chemokines and Their Association With Symptom Severity in Women With Endometriosis 2025
- Role of the gut microbiota in the pathogenesis of endometriosis: a review 2024
- Emerging bioengineering breakthroughs in precision diagnosis and therapy for endometriosis and adenomyosis 2024
- Vitamin D-The Iceberg in Endometriosis-Review and Meta-Analysis 2024
- The role of innate and adaptive immunity in endometriosis 2024
- Impact of oil-based contrast agents in hysterosalpingography on fertility outcomes in endometriosis: a retrospective cohort study 2024
- The Effects of Vitamin D3 Supplementation and Simultaneous Exercise on Aldehyde Dehydrogenase Gene Expression in Endometriosis Female Rats 2023
- Evaluation of expression of biomarkers of PLAGL1 (ZAC1), microRNA, and their non-coding RNAs in patients with endometriosis 2023
- Pain symptoms, sexual and mental health at the time of endometriosis diagnosis 2023
- Histopathologic evaluation of the inflammatory factors and stromal cells in the endometriosis lesions: A case-control study 2022
- Associations between endometriosis and allergy-related diseases as well as different specific immunoglobulin E allergy: A cross-sectional study 2022
- miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis 2021
- Evaluation of Toll-like receptor 3 (TLR3) signaling pathway genes and its genetic polymorphisms in ectopic and eutopic endometrium of women with endometriosis 2021
- Designing a Pragmatic Dose-Escalation for Vitamin-D to Reduce Endometriosis Related Pain after Laparoscopy in Vitamin- D Deficient Women 2021
- The role of mitogen‐activated protein kinase signaling pathway in endometriosis 2021
- Role of Th1, Th2, Th17, and regulatory T cells in endometriosis 2021
- Endometriosis and gynaecological cancers: molecular insights behind a complex machinery 2021
- Auto-immunity and endometriosis 2021
- Endometriosis Associated Infertility: A Critical Review and Analysis on Etiopathogenesis and Therapeutic Approaches 2020
- Actual research trends in etiology and pathogenesis of endometriosis (a review) 2020
- Endometriosis: What is the Influence of Immune Cells? 2020
- TSP1‐CD47‐SIRPα signaling facilitates the development of endometriosis by mediating the survival of ectopic endometrium 2020
- Deep Infiltrating Endometriosis and Activation and Memory Surface Markers and Cytokine Expression in Isolated Treg Cells 2020
- Association between FOXP3+ regulatory T-cells and occurrence of peritoneal lesions in women with ovarian endometrioma and dermoid cysts 2019
- Immunology of Endometriosis; a Systematic Review 2019
- The Origin and Pathogenesis of Endometriosis 2019
- Endometriosis and risk of ovarian cancer: what do we know? 2019
- Differential Levels of Regulatory T Cells and T-Helper-17 Cells in Women With Early and Advanced Endometriosis 2019
- MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target 2018
- Expression of programmed death-1 (PD-1) and its ligand PD-L1 is upregulated in endometriosis and promoted by 17beta-estradiol 2018
- Altered Immunity in Endometriosis: What Came First? 2018
- Treg and NK cells related cytokines are associated with deep rectosigmoid endometriosis and clinical symptoms related to the disease 2018
- The miRNA Mirage: How Close Are We to Finding a Non-Invasive Diagnostic Biomarker in Endometriosis? A Systematic Review 2018
- The link between immunity, autoimmunity and endometriosis: a literature update 2018
- Captação de nanopartícula lipídica marcada radioativamente por receptores de LDL em membrana celular de focos de endometriose 2018
- Pathogenesis of endometriosis: the genetic/epigenetic theory 2018
- Effects of cisplatin on surgically induced endometriosis in a rat model 2018
- Caesarean section scar endometriosis: A case report and review of the literature with special emphasis on malignant transformation 2018
- Analysis of the ectoenzymes ADA, ALP, ENPP1, and ENPP3, in the contents of ovarian endometriomas as candidate biomarkers of endometriosis 2017
- “What do we know about regulatory T cells and endometriosis? A systematic review” 2017
- Drug delivery for the treatment of endometriosis and uterine fibroids 2017
- Avaliação da participação dos <i>Mollicutes</i> e outros microrganismos de interesse genital na endometriose humana. 2017
- Effects of Vitamin D on Endometriosis-Related Pain: A Double-Blind Clinical Trial 2016
- Laparoscopic Surgery: A New Technique to Induce Endometriosis in a Mouse Model 2016
- The gut microbiota: a puppet master in the pathogenesis of endometriosis? 2016
- Signaling LIF and IL-1 pathways changes in patients with peritoneal endometriosis and infertility 2015
- Effect of GuiXiong Xiaoyi Wan in Treatment of Endometriosis on Rats 2015
- Immunological aspects of endometriosis: a review. 2015
- High rate of nickel allergy in women with endometriosis: A 3‐year population‐based study 2015
Source provenance
- europepmc
- last seen: 2026-08-22T06:09:51.966504+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:16:35.898691+00:00
- unpaywall
- last seen: 2026-08-22T06:23:50.750314+00:00
License: CC0
· commercial use OK