The Role of Fertility Preservation in Women with Endometriosis: A Systematic Review

Daniel Lantsberg, Fernando S, Shavi Fernando, Cohen Y, Yoni Cohen, Luk Rombauts
Journal of minimally invasive gynecology · 2019 · vol. 27(2) , pp. 362–372 · doi:10.1016/j.jmig.2019.09.780 · PMID:31546067 · W2974185079
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This systematic review examines fertility preservation options for women with endometriosis, analyzing available treatments and their success rates.

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Abstract

ObjectiveTo summarize the available evidence concerning fertility preservation techniques in the context of women with endometriosis.Data sourcesWe searched for studies published between 1984 and 2019 on endometriosis and Assisted Reproductive Technology outcomes. We searched MEDLINE and PubMed and performed a manual search of reference lists within identified studies.Methods of study selectionA total of 426 articles were identified, and 7 studies were eligible to be included for the systematic review. We included all published studies, excluding reviews, case reports, and animal studies.Tabulation, integration, and resultsDespite a significant increase in the number of studies addressing fertility preservation over the study period, we found a relative lack of evidence addressing the use of fertility preservation techniques in women with endometriosis. The studies identified included 2 case reports, 1 histological science study, and 4 retrospective cohort studies.ConclusionWomen with endometriosis may benefit from fertility preservation techniques. However, there currently is a paucity of data in this population, especially when compared with other indications for fertility preservation. Although much knowledge can be translated from the oncofertility discipline, we have identified and discussed endometriosis-related changes to ovarian reserve and oocyte health that justify further well-designed research to confirm that fertility preservation outcomes are similar for women with endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fertility Preservation Peritoneal Diseases Animals Cohort Studies Endometriosis Endometriosis Endometriosis Female Fertility Preservation Fertility Preservation Humans Ovarian Reserve Ovarian Reserve Peritoneal Diseases Peritoneal Diseases Peritoneal Diseases Reproductive Techniques, Assisted Retrospective Studies Treatment Outcome

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

Cited by (28)

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