Ovarian endometriosis and fertility preservation: a challenge in 2018

Jacques Donnez, Javier García-Solares, Marie-Madeleine Dolmans, Marie‐Madeleine Dolmans
Minerva ginecologica · 2018 · vol. 70(4) , pp. 408–414 · doi:10.23736/s0026-4784.18.04229-6 · PMID:29644329 · W2977407041
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This paper discusses ovarian endometriosis management, emphasizing that stripping and ablation are preferred for infertility to preserve ovarian reserve, and suggesting ovarian tissue autotransplantation or oocyte vitrification for patients at risk of premature ovarian insufficiency.

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Abstract

Endometriosis is a benign, estrogen-dependent gynecological disorder. It is now well established that three different forms of endometriosis can occur in the pelvic cavity, namely peritoneal endometriosis, ovarian endometriosis and deep endometriotic nodules of the rectovaginal septum. Treatment of endometriosis-associated infertility has been investigated using both medical and surgical modalities. Surgery for ovarian endometriosis can lead to premature ovarian insufficiency (POI) and further infertility, so one of the most important goals of therapy should be preserving fertility. Procedures combining stripping and ablation should be considered the first-line approach for ovarian endometrioma-related infertility, in order to protect the ovarian reserve, which may already be depleted even before surgery. Autotransplantation of ovarian tissue should be considered in case of mandatory radical treatment (oophorectomy), or if conservative treatment poses a risk. For patients at risk of POI, particularly those undergoing gonadotoxic treatment, two main fertility preservation options exist: oocyte vitrification or reimplantation of fresh or frozen ovarian tissue. Both have advantages and disadvantages.

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Condition tags

mesh:D004715endometriosisendometriomainfertility

MeSH descriptors

Endometriosis Fertility Preservation Ovarian Diseases Endometriosis Endometriosis Endometriosis Female Fertility Preservation Humans Oocytes Oocytes Ovarian Diseases Ovarian Diseases Ovarian Diseases Ovariectomy Ovariectomy Ovary Ovary Primary Ovarian Insufficiency Primary Ovarian Insufficiency

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (14)

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