Correlative factors associated with the recurrence of ovarian endometriosis: a retrospective study

Xi-Wa Zhao, Xiwa Zhao, Mengmeng Zhang, Jian Zhao, Wei Zhao, Shan Kang
In: Clinical and Experimental Obstetrics & Gynecology · 2021 · vol. 48(4) · doi:10.31083/j.ceog4804152 · W3194421914
article OA: gold CC0 ⤵ 1 in-corpus citation
🔓 Open OA copy View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Previous medical treatment, painful nodules, largest cyst diameter, and bilateral involvement increased ovarian endometriosis recurrence, while postoperative medical treatment and pregnancy reduced it.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Background: The aim of this study was to confirm and analyze the correlative factors that could influence the recurrence of ovarian endometriosis after conservative surgery, including both risk and protective factors. Methods: From January 2010 to January 2018, a retrospective study was conducted which included 1080 patients with ovarian endometriosis who received a minimum of 2 years of follow-up after conservative surgery at a university-based tertiary care hospital. Recurrence was defined as the presence of ovarian cysts larger than 2 cm detected by ultrasonography within 2 years after surgery. The effects of twenty correlative variables on recurrence were evaluated. Results: The cumulative 2-year recurrence rate of ovarian endometriosis after conservative surgery was 15%. According to the logistic regression analysis, the significant risk factors that were independently associated with high recurrence of endometriosis were previous medical treatment of endometriosis (odds ratio [OR] = 2.06; 95% confidence interval [95% CI] = 1.27–3.34; P = 0.004), painful nodules in the pouch of Douglas (OR = 2.44; 95% CI = 1.23–4.85; P = 0.011), largest cyst diameter (OR = 1.54; 95% CI = 1.08–2.18; P = 0.016) and bilateral ovarian involvement (OR = 1.69; 95% CI = 1.19–2.39; P = 0.003). Moreover, the protective factors that were independently associated with low recurrence of endometriosis were postoperative medical treatment (OR = 0.59; 95% CI = 0.42–0.84; P = 0.003) and postoperative pregnancy (OR = 0.34; 95% CI = 0.19–0.62; P < 0.0001). Conclusions: The results of this retrospective analysis of 1080 patients might help predict the prognosis of patients with ovarian endometriosis after conservative surgery and benefit the clinical management of ovarian endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (26)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK