Fertility preservation in women with ovarian endometriosis

Jacques Donnez, Donnez J, Squifflet J, Jean Squifflet, Jadoul P, Pascale Jadoul, Jean-Christophe Lousse, Lousse JC, Marie-Madeleine Dolmans, Dolmans MM, Olivier Donnez, Donnez O
Frontiers in bioscience (Elite edition) · 2011 · vol. E4(1) , pp. 1654 · doi:10.2741/487 · PMID:22201982 · W2071824703
article OA: closed CC0 ⤵ 12 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper discusses fertility preservation in women with severe endometriosis, emphasizing that experienced surgeons are crucial for preserving ovarian tissue during endometrioma removal to improve fertility.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This paper is a focused review discussing fertility preservation strategies in women with severe ovarian endometriosis, highlighting the role of medico-surgical management and the persistent challenge that complete resolution of endometriosis is not possible. It summarizes evidence that laparoscopic cystectomy for endometriomas can be associated with low ovarian reserve, attributing this to excision of normal ovarian tissue along with the cyst wall, and it stresses that ovarian surgery should be performed by experienced surgeons to better preserve fertility. A key caveat is that the article is not a primary study and relies on reported findings and expert considerations rather than new data. This paper is centrally about endometriosis — it focuses specifically on fertility preservation in women with severe ovarian endometriosis and reviews issues after endometrioma surgery.

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Abstract

Endometriosis is one of the most frequently encountered benign diseases in gynecology. Complete resolution of endometriosis is not yet possible, but therapy has essentially three main objectives: (1) to preserve and improve fertility, (2) to reduce pain, and (3) to delay recurrence for as long as possible. The aim of this paper is to focus on fertility preservation in women with severe endometriosis. In moderate and severe endometriosis, a medico-surgical approach remains the gold standard, but more and more papers are reporting a low ovarian reserve after laparoscopic cystectomy for endometriomas. Indeed, very frequently, normal ovarian tissue is excised together with the endometrioma wall. Ovarian surgery in endometriosis patients should therefore be performed by experienced surgeons in order to both preserve and improve fertility. Preservation of ovarian tissue should be considered in all patients at serious risk of future fertility impairment, particularly before any treatment likely to result in ovarian endometriosis recurrence and/or premature ovarian failure.
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Abstract

Endometriosis is one of the most frequently encountered benign diseases in gynecology. Complete resolution of endometriosis is not yet possible, but therapy has essentially three main objectives: (1) to preserve and improve fertility, (2) to reduce pain, and (3) to delay recurrence for as long as possible. The aim of this paper is to focus on fertility preservation in women with severe endometriosis. In moderate and severe endometriosis, a medico-surgical approach remains the gold standard, but more and more papers are reporting a low ovarian reserve after laparoscopic cystectomy for endometriomas. Indeed, very frequently, normal ovarian tissue is excised together with the endometrioma wall. Ovarian surgery in endometriosis patients should therefore be performed by experienced surgeons in order to both preserve and improve fertility. Preservation of ovarian tissue should be considered in all patients at serious risk of future fertility impairment, particularly before any treatment likely to result in ovarian endometriosis recurrence and/or premature ovarian failure.

Keywords

- Ovary - Ovarian Endometriosis - Endometrioma - Fertility Preservation - Cryopreservation - Ovarian Cortex - Review

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Fertility Ovarian Diseases Cryopreservation Endometriosis Female Humans Ovarian Diseases Ovarian Follicle Ovarian Follicle Ovary Ovary

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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