Peripheral Blood Biomarkers for Endometriosis
This chapter reviews current peripheral blood biomarkers including miRNAs, glycoproteins, immunological, angiogenic, and cell adhesion/invasion factors for the diagnosis of endometriosis.
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This paper describes and discusses the current status of peripheral blood biomarkers for endometriosis, focusing on classes such as microRNAs, glycoproteins, immunological markers, angiogenic factors, and cell adhesion/invasion factors, as part of efforts to develop a noninvasive diagnostic test. The high-level premise is that a blood-based assay could discriminate women with endometriosis from those without, but existing diagnostic approaches such as ultrasound may not rule out peritoneal disease. The paper does not present new experimental results; its limitation is that it is a narrative chapter summarizing the state of biomarker research rather than providing validation or performance metrics for any single marker panel. This paper is centrally about endometriosis — it reviews peripheral blood biomarkers proposed for noninvasive diagnosis of endometriosis.
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