Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1α in endometriosis
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This study measured peritoneal fluid levels of thromboxane B2 and 6-keto-prostaglandin F1α in women with and without endometriosis to investigate their roles in the condition.
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Abstract
An anatomic basis for the infertility associated with endometriosis is often lacking. The present study measured peritoneal fluid levels of two of the stable products of prostaglandin endoperoxides (thromboxane B2 and 6-keto-prostaglandin F1 alpha) in patients with and without endometriosis. Both compounds were significantly elevated in the endometriosis group (n = 15, p less than 0.05). This suggests an increase in the peritoneal fluid levels of thromboxane A2 and prostacyclin, both of which could act on tubal smooth muscle and interfere with tubal function. Such altered tubal function might explain the phenomenon of endometriosis-induced infertility when there is no direct damage to the reproductive organs.
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- Identification and analysis of novel endometriosis biomarkers via integrative bioinformatics 2022
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- Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis 2019
- How to Understand the Complexity of Endometriosis-Related Pain 2017
- Management of endometriosis‐related pelvic pain 2017
- The role of the sympathetic nervous system and semaphorins in the pathogenesis of endometriosis 2016
- Endometriose 2016
- Endometriosis-Derived Thromboxane A2 Induces Neurite Outgrowth 2016
- Endometriose: Pathogenese, Symptome und Diagnostik 2015
- The peritoneum—an important factor for pathogenesis and pain generation in endometriosis 2014
- Successful pregnancy in a case of bladder and ovary endometriosis following cystoscopy‐assisted laparoscopic resection 2014
- Induction of the Neurokinin 1 Receptor by TNFα in Endometriotic Tissue Provides the Potential for Neurogenic Control Over Endometriotic Lesion Growth 2013
- Neuroimmunomodulatory Alterations in Non-Lesional Peritoneum Close to Peritoneal Endometriosis 2012
- Effect of antiangiogenic treatment on peritoneal endometriosis-associated nerve fibers 2012
- Cellular and molecular basis for endometriosis-associated infertility 2012
- Relationship Between Toll‐like Receptor‐4 and <scp>mPGES</scp>‐1 Gene Expression in Local Lesions of Endometriosis Patients 2012
- Pathophysiology of Infertility in Endometriosis 2011
- Influence of Nerve Growth Factor in Endometriosis-Associated Symptoms 2011
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- PGE2 and PGF2α release by human peritoneal macrophages in endometriosis 1996
- Pathogenesis of Infertility in Endometriosis 1995
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- Endometrial leukocyte subpopulations in women with endometriosis 1995
- Treatment of Infertility Associated With Endometriosis 1995
- Elevation of the phospholipase A2 activity in peritoneal fluid cells from women with endometriosis 1994
- Aberrant integrin expression in the endometrium of women with endometriosis. 1994
- The Use of Arachidonic Acid in Some Gynaecological Disorders 1994
- Biochemische Aspekte der Endometriose 1993
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