The influence of peritoneal endometriotic lesions on the generation of endometriosis-related pain and pain reduction after surgical excision
This prospective study investigated how different endometriotic lesions, particularly peritoneal implants, influence pain and pain reduction after surgical excision in 44 patients.
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This prospective study investigated how different types of endometriotic lesions, especially peritoneal endometriotic implants, influence pain generation and the magnitude of pain reduction after surgical excision. Fifty-one pre-menopausal patients undergoing laparoscopy for chronic pelvic pain, dysmenorrhoea and/or ovarian cysts were assessed with standardized pre- and post-operative pain scores using a visual analogue scale, and patients with peritoneal endometriosis were stratified by baseline pain score. Patients with peritoneal endometriosis and higher baseline pain (group A) and patients with endometriosis without peritoneal implants (group C) had postoperative pain score decreases of at least two grades, whereas patients without endometriosis (group D) showed no significant reduction. The paper frames this finding with the caveat that reductions were not seen in the no-endometriosis group, limiting interpretation of pain outcomes beyond those with diagnosed disease. This paper is centrally about endometriosis — it specifically evaluates how peritoneal endometriotic lesions affect endometriosis-related pain and pain change after surgical excision.
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Cited by (11)
- The role of the sympathetic nervous system and semaphorins in the pathogenesis of endometriosis 2016
- Hyperalgesiemechanismen bei Patientinnen mit Endometriose 2015
- Systematic review of endometriosis pain assessment: how to choose a scale? 2014
- Analysis of biomarker expression in severe endometriosis and determination of possibilities for targeted intraoperative imaging 2013
- Chronic Pelvic Pain in Endometriosis: An Overview 2013
- Utero-ovarian hemodynamics after laparoscopic treatment of infertility caused by moderate to severe endometriosis 2013
- Influence of Nerve Growth Factor in Endometriosis-Associated Symptoms 2011
- Surgical Therapies: Peritoneal Endometriosis Surgery 2011
- Endometriose und Nervenfasern 2010
- Endometriose und Nervenfasern Ist Endometriose durch den Nachweis von Nervenfasern im Endometrium diagnostizierbar 2010
- Chronic pelvic pain: Cause, diagnosis and therapy from a gynaecologist's and an endoscopist's point of view 2009
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