Endometriose

S Mechsner, Sylvia Mechsner
Schmerz (Berlin, Germany) · 2016 · vol. 30(5) , pp. 477–490 · doi:10.1007/s00482-016-0154-1 · PMID:27681777 · W2549454299
review OA: closed CC0 ⤵ 30 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Endometriosis affects women of reproductive age with symptoms like pain and infertility, impacting quality of life and economics, with high recurrence rates and diagnostic delays due to unknown pathogenesis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper describes endometriosis as a chronic gynecologic disease in women of reproductive age, summarizing key symptoms (e.g., dysmenorrhea, dyspareunia, cyclic and acyclic pelvic pain, bleeding disorders, and infertility), estimated prevalence (2–20%), and major clinical burdens such as reduced quality of life and economic impact. It highlights that more than half of affected women have ongoing treatment needs and that recurrence rates remain high (50–80%) even after surgical and/or hormonal therapy, with a typical delay of 6–8 years between symptom onset and diagnosis, attributed to incomplete understanding of pathogenesis and pain mechanisms plus limited awareness. The paper states no original human or animal studies were performed by the author and notes that knowledge gaps contribute to diagnostic and therapeutic challenges. This paper is centrally about endometriosis — it provides an overview of the disease’s symptoms, epidemiology, diagnostic delay, recurrence, and unresolved pathogenesis/pain mechanisms.

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Condition tags

dyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometriosis Adult Cost of Illness Delayed Diagnosis Diagnosis, Differential Dyspareunia Dyspareunia Dyspareunia Dyspareunia Dysuria Dysuria Dysuria Dysuria Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female

Citation neighborhood

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References (25)

Cited by (30)

Source provenance

europepmc
last seen: 2026-06-16T06:07:01.518242+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:20:49.724109+00:00
License: CC0 · commercial use OK