Endometriosis in Reproductive Years: The Origin of Pain in Endometriosis and Adenomyosis

Sylvia Mechsner
In: Endometriosis and Adenomyosis · 2022 · pp. 199–206 · doi:10.1007/978-3-030-97236-3_15 · W4285276998
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Endometriosis causes manifold pain through peripheral and central sensitization, hormonal, psychological, and muscular changes, leading to both cyclical and atypical symptoms.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper/chapter describes how endometriotic lesions in women of reproductive age can be located in the pelvis as endometriosis or disseminated into the myometrium as adenomyosis, both causing chronic inflammation. It explains that endometriosis-related pain is multi-component, involving nociceptive and nociplastic mechanisms with central sensitization, and it lists both cyclical and atypical symptom patterns (e.g., dysmenorrhea, dyspareunia, bladder/intestinal complaints, and psychological symptoms). The chapter argues that pain origin is complex and includes peripheral and central sensitization as well as hormonal, psychological, and muscular changes, while noting that the broad symptom range often leads patients to consult multiple specialties. This paper is centrally about endometriosis — it specifically discusses the origin and mechanisms of pain in endometriosis and adenomyosis.

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endometriosisadenomyosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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