Schmerztherapie bei Patientinnen mit Endometriose
Endometriosis causes diverse pain, including nociceptive, nociplastic, and central sensitization, leading to cyclical and atypical symptoms that multimodal therapy can significantly improve.
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The paper reviews the spectrum of pain mechanisms in women with endometriosis, describing both nociceptive pain and a nociplastic response with central sensitization that can broaden symptoms beyond classic cyclical complaints. It reports that, alongside severe dysmenorrhea, cyclical lower abdominal pain, dyspareunia, dysuria, and dyschezia, atypical manifestations such as acyclical lower abdominal pain, radiating pain, nonspecific bladder and bowel symptoms, and depression are increasingly seen. It argues that multimodal therapy that accounts for complex pathophysiological changes can significantly improve complex symptoms that limit quality of life, while noting as an article review that it does not present new human or animal study data. This paper is centrally about endometriosis — it focuses on endometriosis-associated pain phenotypes and recommends a multimodal, mechanism-informed approach for managing these symptoms.
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Cited by (1)
- Endometriose 2025
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00