{"paper_id":"dc3d84d6-87f9-4e6d-a4b6-75cee5e1cef1","body_text":"Zusammenfassung\nDie durch Endometriose bedingten Schmerzphänomene sind vielfältig. Neben nozizeptiven Schmerzen kommt es auch zu einer noziplastischen Reaktion mit zentraler Sensitivierung. Daher treten neben den klassischen zyklischen Beschwerden wie schwerer Dysmenorrhö, zyklischen Unterbauchschmerzen, Dyspareunie, Dysurie und Dyschezie auch zunehmend atypische Schmerzen wie azyklische Unterbauchschmerzen, Ausstrahlung der Schmerzen, unspezifische Blasen- und Darmbeschwerden oder auch Depressionen auf. Mithilfe einer multimodalen Therapie unter Berücksichtigung der komplexen pathophysiologischen Veränderungen können die komplexen Beschwerden, die die Lebensqualität signifikant einschränken, deutlich verbessert werden.\nAbstract\nThe pain phenomena caused by endometriosis are diverse. In addition to nociceptive pain, patients also experience a nociplastic reaction with central sensitization. Therefore, in addition to the classic cyclical symptoms such as severe dysmenorrhea, cyclical lower abdominal pain, dyspareunia, dysuria, and dyschezia, there is also an increasing occurrence of atypical pain such as acyclical lower abdominal pain, radiating pain, non-specific bladder and bowel symptoms, and even depression. Multimodal therapy that takes into account the complex pathophysiological changes is able to significantly improve the complex symptoms that significantly limit quality of life.\nSimilar content being viewed by others\nLiteratur\nArmour M, Ferfolja T, Curry C et al (2020) The prevalence and educational impact of pelvic and menstrual pain in Australia: a national online survey of 4202 young women aged 13–25 years. J Pediatr Adolesc Gynecol 33:511–518\nBallweg ML (2004) Impact of endometriosis on women’s health: comparative historical data show that the earlier the onset, the more severe the disease. 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Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.\nAdditional information\nRedaktion\nLudwig Kiesel, Münster\nWolfgang Küpker, Baden-Baden\nRicardo Felberbaum, Kempten\nBrigitte Leeners, Zürich\nQR-Code scannen & Beitrag online lesen\nRights and permissions\nAbout this article\nCite this article\nMechsner, S. Schmerztherapie bei Patientinnen mit Endometriose. Gynäkologische Endokrinologie 21, 176–183 (2023). https://doi.org/10.1007/s10304-023-00520-7\nAccepted:\nPublished:\nVersion of record:\nIssue date:\nDOI: https://doi.org/10.1007/s10304-023-00520-7\nSchlüsselwörter\n- Nozizeptiver Schmerz\n- Noziplastischer Schmerz\n- Zentrale Sensitivierung\n- Chronischer Schmerz\n- Multimodale Therapie","source_license":"CC0","license_restricted":false}