Schmerztherapie bei Patientinnen mit Endometriose

Sylvia Mechsner
In: Die Gynäkologie · 2024 · vol. 57(3) , pp. 154–161 · doi:10.1007/s00129-023-05194-7 · W4390871563
article OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

Endometriosis causes diverse nociceptive and nociplastic pain with central sensitization, leading to cyclical and atypical symptoms that multimodal therapy can significantly improve.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This paper discusses the spectrum of pain mechanisms in women with endometriosis, emphasizing that symptoms include both nociceptive pain and nociplastic pain with central sensitization, producing classic cyclical complaints as well as atypical, non-cyclical pain presentations (e.g., radiating pelvic pain, non-specific bladder/bowel symptoms) and even depression. It describes a multimodal pain-therapy approach that accounts for complex pathophysiology to improve quality-of-life-limiting symptoms. A key limitation explicitly implied by the article format is that it is not presented as new primary clinical trial data but as a narrative/clinical overview that does not provide quantifiable effectiveness estimates. This paper is centrally about endometriosis — it focuses on pain phenotypes (nociceptive and nociplastic/central sensitization) and outlines multimodal pain management strategies for endometriosis-related symptoms.

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last seen: 2026-06-10T17:14:06.276822+00:00
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