Prolactin secretion in endometriotic patients

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This study investigated prolactin secretion patterns in patients diagnosed with endometriosis.

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Abstract

ObjectiveTo clarify a significance of prolactin (PRL) for infertility in endometriosis.Study designsFor seventy endometriotic patients with or without infertility, serum PRL concentrations measured by radioimmunoassay before and 30 min after 500 micrograms of thyrotropin-releasing hormone (TRH) injection were analyzed in relation to the Revised American Fertility Society score in endometriosis as well as to the outcome of the treatment for endometriotic infertility.ResultsWhile no significant relationship was found between the basal PRL levels and the stage of endometriosis or the outcome of the treatment for infertility, the PRL value after TRH injection was significantly greater in the patients who did not become pregnant than those who did (P < 0.05).ConclusionsOccult hyperprolactinemia may be involved in infertility in endometriotic patients.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Prolactin Adolescent Adult Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Infertility, Female Pregnancy Prolactin Thyrotropin-Releasing Hormone Treatment Outcome

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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