The Role of Prolactin– and Endometriosis-Associated Infertility

Hongbo Wang, Nowiah Gorpudolo, Barry Behr
Obstetrical & gynecological survey · 2009 · vol. 64(8) , pp. 542–547 · doi:10.1097/ogx.0b013e3181ab5479 · PMID:19624865 · W2060082358
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This review examines the relationship between prolactin levels, prolactin receptors, and various factors in endometriosis-associated infertility based on existing literature.

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Abstract

UNLABELLED: This review will address the current understanding of the relationship between prolactin (PRL) and endometriosis-associated infertility. Although the exact mechanisms of action of hyperprolactinemia in patients with endometriosis-associated infertility have not been clearly established, this report reviews results from relevant studies in the literature. These include serum PRL levels in endometriosis-associated infertility, PRL receptors in ectopic endometriotic tissues, basal PRL levels after TSH and Danazol (isoxazolic derivative of the synthetic steroid 5alpha-ethinyl-testosterone) therapy, peritoneal fluid and nocturnal serum PRL levels in endometriosis, infertility, and luteal phase PRL concentrations in patients with endometriosis. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this article, the reader should be able to explain the relationship between prolactin- and endometriosis-associated infertility, relate endometriosis with infertility, and summarize two ways in which prolactin and endometriosis may be linked in the pathophysiology of infertility.

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Condition tags

mesh:D004715endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Prolactin Danazol Danazol Endometriosis Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Prolactin Prolactin Prolactin Receptors, Prolactin Receptors, Prolactin

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (19)

Cited by (13)

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License: CC0 · commercial use OK