Peritoneal fluid prolactin in infertile women with endometriosis: lack of evidence of secretory activity by endometrial implants

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This study investigated peritoneal fluid prolactin levels in infertile women with endometriosis to assess endometrial implant secretory activity.

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Abstract

To evaluate the functional status of endometriotic implants, a luteal secretory product of endometrium, PRL, was measured in the PF of 27 infertile women with endometriosis, 13 infertile women without endometriosis, and 11 fertile women undergoing elective sterilization. PF PRL concentrations and PF/plasma PRL ratios were similar in all the groups and did not vary with the menstrual cycle or the stage of endometriosis. These data demonstrate that the ectopic endometrium in infertile women with endometriosis does not secrete PRL in amounts sufficient to elevate PF concentrations and suggest that the infertility observed in these women is probably not dependent upon the secretory activity of endometriotic implants.

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Condition tags

endometriosis

MeSH descriptors

Body Fluids Endometriosis Infertility, Female Peritoneal Cavity Peritoneal Neoplasms Prolactin Adult Body Fluids Endometriosis Endometriosis Female Humans Infertility, Female Peritoneal Neoplasms Peritoneal Neoplasms Prolactin Prolactin

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