Prolactin and pain of endometriosis

Grace J Lee; Frank Porreca; Edita Navratilova

doi:10.1016/j.pharmthera.2023.108435

Prolactin and pain of endometriosis

Grace J Lee, Frank Porreca, Edita Navratilova

Pharmacology & therapeutics · 2023 · vol. 247 , pp. 108435 · doi:10.1016/j.pharmthera.2023.108435 · PMID:37169264 · PMC12181984 · W4375948058

review OA: green CC0 ⤵ 9 in-corpus citations

📄 Open PDF View on OpenAlex View on PubMed View at publisher

⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper investigates the relationship between prolactin levels and the severity of endometriosis-related pain.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Chronic Pain Chronic Pain Chronic Pain Chronic Pain Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Female Female Female Humans Humans Humans Humans Pelvic Pain Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (100)

A deep insight into pelvic pain and endometriosis: a review of the literature from pathophysiology to clinical expressions via openalex
A pilot study to evaluate the clinical relevance of endometriosis-associated nerve fibers in peritoneal endometriotic lesions via openalex
A psychological profile of endometriosis patients in comparison to patients with pelvic pain of other origins via openalex
Aromatase expression in endometriotic tissues and its relationship to clinical and analytical findings via openalex
Association between endometriosis and hyperprolactinemia in infertile women. via openalex
ATR-IR Spectroscopy Application to Diagnostic Screening of Advanced Endometriosis via openalex
Chronic Pelvic Pain in Women via openalex
Clinical and diagnostic features of different forms of genital endometriosis in female adolescents via openalex
Combined hysteroscopic and laparoscopic findings in patients with chronic pelvic pain via openalex
Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis via openalex
Diagnostic Significance of Selected Serum Inflammatory Markers in Women with Advanced Endometriosis via openalex
Does Cabergoline Help in Decreasing Chronic Pelvic Pain Due to Endometriosis Compared to Medroxyprogesterone Acetate? A Prospective Randomized Study via openalex
Does Cabergoline help in decreasing endometrioma size compared to LHRH agonist? A prospective randomized study via openalex
Dopamine agonists as genital endometriosis target therapy via openalex
Downregulation of CD36 results in reduced phagocytic ability of peritoneal macrophages of women with endometriosis via openalex
Effects of hyperprolactinemia treatment with the dopamine agonist quinagolide on endometriotic lesions in patients with endometriosis-associated hyperprolactinemia via openalex
Endometrial prolactin in hyperprolactinemic women via openalex
Endometriosis via openalex
Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis via openalex
Endometriosis-associated nerve fibers, peritoneal fluid cytokine concentrations, and pain in endometriotic lesions from different locations via openalex
Endometriosis: pathogenesis and treatment via openalex
Expression of Protein Markers of Adipogenesis in Endometriotic Lesions via openalex
Higher levels of prolactin are associated with endometriosis in infertile women. A controlled prospective study via openalex
Hyperinnervation in Intestinal Deep Infiltrating Endometriosis via openalex
Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries via openalex
Increased activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages of patients with endometriosis via openalex
Increased frequency of human leukocyte antigen–E inhibitory receptor CD94/NKG2A–expressing peritoneal natural killer cells in patients with endometriosis via openalex
Inflammation of the adipose tissue in the retroperitoneal cavity adjacent to pelvic endometriosis via openalex
Inflammatory Mediators and Pain in Endometriosis: A Systematic Review via openalex
Mass-forming Retroperitoneal Endometriosis Including a Fat Component: A Diagnostic Dilemma via openalex
Mechanisms of pain in endometriosis via openalex
Nerve fibres in peritoneal endometriosis via openalex
Neurogenic Inflammation in the Context of Endometriosis—What Do We Know? via openalex
NK Cells as Potential Targets for Immunotherapy in Endometriosis via openalex
Nonhormonal therapy for endometriosis: a randomized, placebo-controlled, pilot study of cabergoline versus norethindrone acetate via openalex
Pathogenesis of Endometriosis: The Origin of Pain and Subfertility via openalex
Peritoneal fluid prolactin in infertile women with endometriosis: lack of evidence of secretory activity by endometrial implants via openalex
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? via openalex
Prolactin and cortisol levels in women with endometriosis via openalex
Prolactin hyperstimulation in response to thyrotropin-releasing hormone in patients with endometriosis via openalex
Psychological aspects of endometriosis: Differences between patients with or without pain on four psychological variables via openalex
Relationship between 17-ß-estradiol and prolactin in the regulation of natural killer cell activity during progression of endometriosis via openalex
Retrograde menstruation in healthy women and in patients with endometriosis. via openalex
Risk of developing major depression and anxiety disorders among women with endometriosis: A longitudinal follow-up study via openalex
Salivary cortisol concentrations, stress and quality of life in women with endometriosis and chronic pelvic pain via openalex
Serum anti-Mullerian hormone, prolactin and estradiol concentrations in infertile women with endometriosis via openalex
Stress Exacerbates Endometriosis Manifestations and Inflammatory Parameters in an Animal Model via openalex
Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity via openalex
Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink? via openalex
The Interplay Between Prolactin and Reproductive System: Focus on Uterine Pathophysiology via openalex
The management of menopause in women with a history of endometriosis: a systematic review via openalex
The Role of the Immune System in the Development of Endometriosis via openalex
W2521913548 via openalex
W2549356601 via openalex
W2754843766 via openalex
W2810127666 via openalex
W2889103523 via openalex
W2925631398 via openalex
W2941009385 via openalex
W2952252500 via openalex
W2955415153 via openalex
W2972638203 via openalex
W2977306621 via openalex
W2991792334 via openalex
W2996095329 via openalex
W2996104446 via openalex
W3004643744 via openalex
W3011343577 via openalex
W3039522688 via openalex
W3092324413 via openalex
W3094254450 via openalex
W3118799583 via openalex
W3138310504 via openalex
W3199577057 via openalex
W3202177173 via openalex
W3214723011 via openalex
W4200046914 via openalex
W4205551180 via openalex
W4211081176 via openalex
W4214754424 via openalex
W4220706479 via openalex
W4234160457 via openalex
W4283766077 via openalex
W4294215472 via openalex
W4315435633 via openalex
W4318668124 via openalex
W4319461157 via openalex
W6628680024 via openalex
W6629987096 via openalex
W6653289028 via openalex
W6658538239 via openalex
W6662013558 via openalex
W6682962186 via openalex
W6760522133 via openalex
W6784574998 via openalex
W134345426 via openalex
W6810657829 via openalex
W1526791673 via openalex
W1967133593 via openalex
W1968481775 via openalex

Cited by (9)

Source provenance

europepmc: last seen: 2026-06-12T06:13:51.797165+00:00
openalex: last seen: 2026-06-10T17:14:06.276822+00:00
pubmed: last seen: 2026-05-17T00:33:41.425141+00:00

License: CC0 · commercial use OK

[1] A deep insight into pelvic pain and endometriosis: a review of the literature from pathophysiology to clinical expressions via openalex

[2] A pilot study to evaluate the clinical relevance of endometriosis-associated nerve fibers in peritoneal endometriotic lesions via openalex

[3] A psychological profile of endometriosis patients in comparison to patients with pelvic pain of other origins via openalex

[4] Aromatase expression in endometriotic tissues and its relationship to clinical and analytical findings via openalex

[5] Association between endometriosis and hyperprolactinemia in infertile women. via openalex

[6] ATR-IR Spectroscopy Application to Diagnostic Screening of Advanced Endometriosis via openalex

[7] Chronic Pelvic Pain in Women via openalex

[8] Clinical and diagnostic features of different forms of genital endometriosis in female adolescents via openalex

[9] Combined hysteroscopic and laparoscopic findings in patients with chronic pelvic pain via openalex

[10] Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis via openalex

[11] Diagnostic Significance of Selected Serum Inflammatory Markers in Women with Advanced Endometriosis via openalex

[12] Does Cabergoline Help in Decreasing Chronic Pelvic Pain Due to Endometriosis Compared to Medroxyprogesterone Acetate? A Prospective Randomized Study via openalex

[13] Does Cabergoline help in decreasing endometrioma size compared to LHRH agonist? A prospective randomized study via openalex

[14] Dopamine agonists as genital endometriosis target therapy via openalex

[15] Downregulation of CD36 results in reduced phagocytic ability of peritoneal macrophages of women with endometriosis via openalex

[16] Effects of hyperprolactinemia treatment with the dopamine agonist quinagolide on endometriotic lesions in patients with endometriosis-associated hyperprolactinemia via openalex

[17] Endometrial prolactin in hyperprolactinemic women via openalex

[18] Endometriosis via openalex

[19] Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis via openalex

[20] Endometriosis-associated nerve fibers, peritoneal fluid cytokine concentrations, and pain in endometriotic lesions from different locations via openalex

[21] Endometriosis: pathogenesis and treatment via openalex

[22] Expression of Protein Markers of Adipogenesis in Endometriotic Lesions via openalex

[23] Higher levels of prolactin are associated with endometriosis in infertile women. A controlled prospective study via openalex

[24] Hyperinnervation in Intestinal Deep Infiltrating Endometriosis via openalex

[25] Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries via openalex

[26] Increased activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages of patients with endometriosis via openalex

[27] Increased frequency of human leukocyte antigen–E inhibitory receptor CD94/NKG2A–expressing peritoneal natural killer cells in patients with endometriosis via openalex

[28] Inflammation of the adipose tissue in the retroperitoneal cavity adjacent to pelvic endometriosis via openalex

[29] Inflammatory Mediators and Pain in Endometriosis: A Systematic Review via openalex

[30] Mass-forming Retroperitoneal Endometriosis Including a Fat Component: A Diagnostic Dilemma via openalex

[31] Mechanisms of pain in endometriosis via openalex

[32] Nerve fibres in peritoneal endometriosis via openalex

[33] Neurogenic Inflammation in the Context of Endometriosis—What Do We Know? via openalex

[34] NK Cells as Potential Targets for Immunotherapy in Endometriosis via openalex

[35] Nonhormonal therapy for endometriosis: a randomized, placebo-controlled, pilot study of cabergoline versus norethindrone acetate via openalex

[36] Pathogenesis of Endometriosis: The Origin of Pain and Subfertility via openalex

[37] Peritoneal fluid prolactin in infertile women with endometriosis: lack of evidence of secretory activity by endometrial implants via openalex

[38] Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? via openalex

[39] Prolactin and cortisol levels in women with endometriosis via openalex

[40] Prolactin hyperstimulation in response to thyrotropin-releasing hormone in patients with endometriosis via openalex

[41] Psychological aspects of endometriosis: Differences between patients with or without pain on four psychological variables via openalex

[42] Relationship between 17-ß-estradiol and prolactin in the regulation of natural killer cell activity during progression of endometriosis via openalex

[43] Retrograde menstruation in healthy women and in patients with endometriosis. via openalex

[44] Risk of developing major depression and anxiety disorders among women with endometriosis: A longitudinal follow-up study via openalex

[45] Salivary cortisol concentrations, stress and quality of life in women with endometriosis and chronic pelvic pain via openalex

[46] Serum anti-Mullerian hormone, prolactin and estradiol concentrations in infertile women with endometriosis via openalex

[47] Stress Exacerbates Endometriosis Manifestations and Inflammatory Parameters in an Animal Model via openalex

[48] Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity via openalex

[49] Surgical removal of superficial peritoneal endometriosis for managing women with chronic pelvic pain: time for a rethink? via openalex

[50] The Interplay Between Prolactin and Reproductive System: Focus on Uterine Pathophysiology via openalex

[51] The management of menopause in women with a history of endometriosis: a systematic review via openalex

[52] The Role of the Immune System in the Development of Endometriosis via openalex

[53] W2521913548 via openalex

[54] W2549356601 via openalex

[55] W2754843766 via openalex

[56] W2810127666 via openalex

[57] W2889103523 via openalex

[58] W2925631398 via openalex

[59] W2941009385 via openalex

[60] W2952252500 via openalex

[61] W2955415153 via openalex

[62] W2972638203 via openalex

[63] W2977306621 via openalex

[64] W2991792334 via openalex

[65] W2996095329 via openalex

[66] W2996104446 via openalex

[67] W3004643744 via openalex

[68] W3011343577 via openalex

[69] W3039522688 via openalex

[70] W3092324413 via openalex

[71] W3094254450 via openalex

[72] W3118799583 via openalex

[73] W3138310504 via openalex

[74] W3199577057 via openalex

[75] W3202177173 via openalex

[76] W3214723011 via openalex

[77] W4200046914 via openalex

[78] W4205551180 via openalex

[79] W4211081176 via openalex

[80] W4214754424 via openalex

[81] W4220706479 via openalex

[82] W4234160457 via openalex

[83] W4283766077 via openalex

[84] W4294215472 via openalex

[85] W4315435633 via openalex

[86] W4318668124 via openalex

[87] W4319461157 via openalex

[88] W6628680024 via openalex

[89] W6629987096 via openalex

[90] W6653289028 via openalex

[91] W6658538239 via openalex

[92] W6662013558 via openalex

[93] W6682962186 via openalex

[94] W6760522133 via openalex

[95] W6784574998 via openalex

[96] W134345426 via openalex

[97] W6810657829 via openalex

[98] W1526791673 via openalex

[99] W1967133593 via openalex

[100] W1968481775 via openalex