Increased activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages of patients with endometriosis

Jean-Christophe Lousse, Lousse JC, Jean‐Christophe Lousse, Van Langendonckt A, Anne Van Langendonckt, González-Ramos R, Reinaldo González-Ramos, Defrère S, Sylvie Defrère, Renkin E, Emmanuelle Renkin, Donnez J, Jacques Donnez
Fertility and sterility · 2007 · vol. 90(1) , pp. 217–220 · doi:10.1016/j.fertnstert.2007.06.015 · PMID:17889859 · W2085484171
article OA: closed CC0 ⤵ 86 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated the activation of nuclear factor-kappa B (NF-κB) in isolated peritoneal macrophages from endometriosis patients and found increased levels compared to controls.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Endometriosis is characterized by pelvic inflammation that shows an increased number of activated peritoneal macrophages and their secreted products such as cytokines, growth factors, and angiogenic factors. Our results show that activation of nuclear factor-kappa B (NF-kappaB), a pro-inflammatory transcription factor, is statistically significantly increased in peritoneal macrophages from patients with endometriosis when compared with controls.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Macrophage Activation Macrophages, Peritoneal Transcription Factor RelA Adult Case-Control Studies Cell Nucleus Cell Nucleus Endometriosis Female Humans Immunohistochemistry Macrophages, Peritoneal Severity of Illness Index Transcription Factor RelA

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (22)

Cited by (50)

Source provenance

europepmc
last seen: 2026-07-30T06:25:42.655704+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:48.452140+00:00
License: CC0 · commercial use OK