[Research progress on the role of epithelial-mesenchymal transition in pathogenesis of endometriosis].
Epithelial-mesenchymal transition and mesenchymal-epithelial transition are critical to endometriosis pathogenesis, influencing lesion formation, fibrosis, invasion, and metastasis.
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The paper is a research-progress review examining how epithelial–mesenchymal transition (EMT) may contribute to the pathogenesis of endometriosis, synthesizing existing findings rather than presenting new experimental data. It discusses EMT-related mechanisms and the ways epithelial cells could adopt mesenchymal phenotypes in this disease context, while noting limitations typical of reviews, such as reliance on heterogeneous, previously published studies and the lack of a single unifying evidence base. No specific population, experimental protocol, or quantified outcomes are described in the provided text, reflecting its narrative, literature-focused format. This paper is centrally about endometriosis — focusing on the role of epithelial–mesenchymal transition in endometriosis pathogenesis.
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Cited by (4)
- Research advances in endometriosis-related signaling pathways: A review 2023
- JARID2 regulates epithelial mesenchymal transition through the PTEN/AKT signalling pathways in ovarian endometriosis 2023
- Analysis of the relationship between COMT polymorphisms and endometriosis susceptibility 2019
- CYP17A1 rs743572 polymorphism might contribute to endometriosis susceptibility 2018
Source provenance
- europepmc
- last seen: 2026-06-12T06:13:51.797165+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:20:43.714878+00:00