Nocturnal prolactin levels in infertile women with endometriosis.

Ewa Radwańska, Israel Henig, W. Paul Dmowski
In: PubMed · 1987 · vol. 32(8) , pp. 605–8 · W2416172144
article OA: closed CC0 ⤵ 9 in-corpus citations Metadata only
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study investigated nocturnal prolactin levels in infertile women with endometriosis and found an exaggerated and prolonged nocturnal prolactin peak, potentially contributing to infertility.

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Abstract

Both hyperprolactinemia and endometriosis are associated with infertility. A study was performed to ascertain whether sleep-related prolactin (PRL) hypersecretion was present in endometriosis. Fifty-five consecutive infertile women with regular menstrual cycles and admitted for diagnostic laparoscopy were studied. Blood samples were drawn throughout the night preceding surgery. Serum PRL, estradiol and progesterone levels were measured with radioimmunoassays. Nocturnal patterns of PRL secretion may be altered in infertile women with endometriosis, with an exaggerated and prolonged nocturnal peak. This alteration in PRL dynamics may contribute to infertility in women with endometriosis and may be a part of the pathophysiology of this disease.

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Condition tags

endometriosisinfertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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