Genetic factors related to endometriosis: present and future

Anna Maria Di Blasio, Edgardo Somigliana, Paola Viganò
In: Expert Review of Obstetrics & Gynecology · 2007 · vol. 2(6) , pp. 791–801 · doi:10.1586/17474108.2.6.791 · W2124847401
OA: closed CC0
View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This paper reviews current research on identifying genetic variations associated with endometriosis susceptibility and discusses future directions for understanding pathogenesis and developing personalized therapies.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Endometriosis is a multifactorial disease that affects 6–10% of women of reproductive age. Epidemiological studies indicate that it is a polygenic disorder, with recurrence risks in first-degree relatives of approximately 2–9%. Thus, the current task of different research groups is to identify genetic variations in an obvious candidate gene that could be associated with an increased susceptibility to endometriosis. The great advancement in molecular biology techniques certainly make this task possible, although particular attention needs to be paid to study design in order to achieve solid results. The data obtained by such studies will allow us to expand our knowledge of the pathogenesis of the disease and, more importantly, develop individualized therapies and prevention strategies to apply to high-risk populations.

My notes (saved in your browser only)

Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (100)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-10-15T06:24:24.424788+00:00
License: CC0 · commercial use OK