Adenomyosis: what is the impact on fertility?

Matalliotakis IM, Ioannis Matalliotakis, Ioannis M Matalliotakis, Katsikis IK, Ilias Katsikis, Ilias K Katsikis, Panidis DK, Dimitrios Panidis, Dimitrios K Panidis
Current opinion in obstetrics & gynecology · 2005 · vol. 17(3) , pp. 261–264 · doi:10.1097/01.gco.0000169103.85128.c0 · PMID:15870560 · W2012914257
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This review examines uterine adenomyosis as a factor in female infertility, discussing its clinical presentation, effects, and treatment options for women desiring future pregnancy.

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Abstract

PURPOSE OF REVIEW: This review is timely and relevant for several reasons. The incidence of adenomyosis begins to rise from the mid-thirties. Moreover, more women are delaying their first pregnancy until later in their thirties or forties, and consequently adenomyosis is encountered more frequently in the fertility clinic during diagnostic work-up. Furthermore, it is difficult to diagnose adenomyosis before surgery, because there are no pathognomonic signs, symptoms or physical findings. Finally, reference data are very limited. RECENT FINDINGS: This review refers to adenomyosis of the uterus as a factor in female infertility. The clinical presentation of adenomyosis uteri is also reviewed, as well as animal and human studies concerning the effect of adenomyosis in female infertility. Different treatment options are discussed, especially those referring to patients who wish to maintain their fecundity. SUMMARY: Uterine adenomyosis remains a fairly frequent and debilitating disease that will be encountered with increasing incidence in the infertile female population. While spectacular advances have been made in recent years in the non-invasive diagnosis of the condition, non-surgical treatment options for infertile patients with adenomyosis arise but need to be confirmed in larger series.
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Adenomyosis: what is the impact on fertility? - Ioannis M Matalliotakis - Ilias K Katsikis - Dimitrios K Panidis Purpose of review This review is timely and relevant for several reasons. The incidence of adenomyosis begins to rise from the mid-thirties. Moreover, more women are delaying their first pregnancy until later in their thirties or forties, and consequently adenomyosis is encountered more frequently in the fertility clinic during diagnostic work-up. Furthermore, it is difficult to diagnose adenomyosis before surgery, because there are no pathognomonic signs, symptoms or physical findings. Finally, reference data are very limited. Recent findings This review refers to adenomyosis of the uterus as a factor in female infertility. The clinical presentation of adenomyosis uteri is also reviewed, as well as animal and human studies concerning the effect of adenomyosis in female infertility. Different treatment options are discussed, especially those referring to patients who wish to maintain their fecundity. Summary Uterine adenomyosis remains a fairly frequent and debilitating disease that will be encountered with increasing incidence in the infertile female population. While spectacular advances have been made in recent years in the non-invasive diagnosis of the condition, non-surgical treatment options for infertile patients with adenomyosis arise but need to be confirmed in larger series.

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Condition tags

endometriosisadenomyosisinfertility

MeSH descriptors

Endometriosis Endometriosis Infertility, Female Animals Embolization, Therapeutic Endometriosis Endometriosis Female Fertility Agents, Female Fertility Agents, Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Infertility, Female

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (43)

Cited by (50)

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License: CC0 · commercial use OK