Polymorphisms in MMP-2 and MMP-9 promoter regions are associated with endometriosis

Observational OA: bronze CC0 ⤵ 32 in-corpus citations
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study investigated the association between polymorphisms in the MMP-2 and MMP-9 promoter regions and endometriosis.

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Abstract

In this case-control study, we investigated the potential associations of MMP-2 and MMP-9 gene promoter region polymorphisms as well as MMP-2 promoter haplotypes with susceptibility to endometriosis in women of caucasian origin. The results demonstrated that polymorphisms in MMP-2 (-735 C/T) and MMP-9 (-1562 C/T) were associated with elevated risk of endometriosis and that certain MMP-2 promoter haplotypes were more common in control group.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Matrix Metalloproteinase 2 Matrix Metalloproteinase 9 Polymorphism, Genetic Polymorphism, Genetic Promoter Regions, Genetic Promoter Regions, Genetic Promoter Regions, Genetic Uterine Diseases Adolescent Adolescent Adult Adult Case-Control Studies Case-Control Studies Endometriosis Endometriosis Female Female Genetic Linkage

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (19)

Cited by (32)

Source provenance

europepmc
last seen: 2026-10-17T06:09:56.316927+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:07:19.155540+00:00
License: CC0 · commercial use OK