Pituitary Gonadotropin Inhibitory Activity of Danazol
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Danazol was investigated for its potential to inhibit pituitary gonadotropin release and was found to possess such activity.
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References (10)
- Clinical Studies with an Antigonadotropin-Danazol via openalex
- Danazol—a Synthetic Steroid Derivative with Interesting Physiologic Properties via openalex
- Pituitary and Testicular Function Studies. I. Experience with a New Gonadal Inhibitor, 17α-Pregn-4-en-20-yno-(2,3-d) isoxazol-17-ol (Danazol)<sup>1</sup> via openalex
- The treatment of endometriosis with Danazol. via openalex
- doi:10.1021/jm00337a001 via openalex
- doi:10.1098/rspb.1937.0004 via openalex
- doi:10.1152/physrev.1945.25.2.203 via openalex
- doi:10.3181/00379727-83-20301 via openalex
- doi:10.1113/jphysiol.1934.sp003217 via openalex
- doi:10.1210/endo-24-1-35 via openalex
Cited by (50)
- Microbial transformation of danazol with Cunninghamella blakesleeana and anti-cancer activity of danazol and its transformed products 2015
- Reversible Inhibition of Spermatogenesis by Danazol with Combination of Testosterone enanthate in Rabbit 2009
- Danazol regulates the functions of normal human endometrial stromal cell subpopulations by modifying endometrial cytokine networks 2009
- A Benefit-Risk Assessment of Medical Treatment for Uterine Leiomyomas 2002
- Danazol enhances Fas-mediated apoptosis in human endometrial epithelial cells within normal physiology 1998
- Pain recurrence: A quality of life issue in endometriosis 1995
- Goserelin (Zoladex) versus danazol for endometriosis: the North American experience 1994
- Effects of danazol on DNA synthesis in rat prostate 1993
- The effect of danazol on tumour control and weight loss in patients on tamoxifen therapy for advanced breast cancer: A randomised double-blind placebo controlled trial 1993
- Effects of Danazol on endometrial DNA synthesis in rats 1993
- Inhibitory and stimulatory actions of danazol in rat ovarian and uterine tissues 1992
- Suppression of the development of uterine adenomyosis by danazol treatment in mice 1992
- Progesterone receptor induction by danazol in cultured cancer cells and the rat uterus 1992
- Studies on the mechanism of action of danazol and gestrinone (R2323) in the rat: evidence for a masked estrogen component* 1989
- Inhibition of gonadotropin-releasing hormone receptors in rat anterior pituitary monolayer cell cultures by danazol 1986
- Danazol and fetal masculinization: a warning 1985
- Danazol treatment of endometriosis: long-term follow-up 1985
- Danazol binding to steroid receptors in human uterine endometrium 1984
- Short‐term effects of danazol on endometrial histology 1984
- Effect of danazol on serum concentrations of pituitary gonadotropins in postmenopausal women 1984
- The effect of danazol on gonadotropin secretion during the follicular phase of the menstrual cycle 1983
- Effects of ethinylestradiol and danazol on embryo survival and implantation in mated beagle bitches. 1983
- Danazol 1982
- Effects of danazol on gonadal steroidogenesis in patients with a complete form of testicular feminization 1982
- In Vitro Effect of Danazol on Luteinizing Hormone-Releasing Hormone-Stimulated Luteinizing Hormone Release in Rat Anterior Pituitary Cell Cultures in Vitro * 1981
- Actions of danazol in vivo on cytochrome P-450 and steroidogenic enzymes in rat testis and liver microsomal preparations 1981
- Danazol suppression of luteinizing hormone secretion: a role for danazol-androgen receptor interaction within the brain-pituitary complex 1981
- Transient Adrenogenital Syndrome due to Exposure to Danazol in Utero 1981
- Changes of Prolactin Secretion Following Long-Term Danazol Application 1981
- Dosage aspects of danazol therapy in endometriosis: Short-term and long-term effectiveness 1981
- Cholesterol, High Density Lipoprotein and Danazol 1981
- Pharmacology and Pharmacokinetics of Danazol 1980
- Review: The Mechanism of Action of Danazol, a Novel Steroid Derivative 1980
- Competitive inhibition by Danazol of oestradiol binding to rabbit and ovine uterine oestradiol receptor 1980
- Evidence that danazol inhibits gonadotropin-induced ovarian steroidogenesis at a point distal to gonadotropin-receptor interaction and adenosine 3′,5′ cyclic monophosphate formation 1980
- Inhibition of Adrenal Steroidogenesis by Danazol in Vivo 1980
- Danazol Binding to Rat Androgen, Glucocorticoid, Progesterone, and Estrogen Receptors: Correlation With Biologic Activity 1979
- Danazol increasingly used. 1979
- Increased Accumulation of Estrogen Receptors in Pituitary Nuclei of Danazol Treated Rats 1979
- A radioimmumoassay for danazol (17α-Pregna-2,4-Dien-20-Yno[2,3-d]Isoxazol-17-OL) 1978
- Effects of Danazol on gonadotropin secretion after ovariectomy in rats 1978
- Fertility in the Rhesus Monkey Following Long-Term Inhibition of Ovarian Function with Danazol 1978
- Radioimmunoassay for Danazol in Human and Monkey Plasma 1978
- Danazol effects on gowadotrop in basal levels and pituitary responsiveness to lh-rn in immature male rats 1978
- Effects of Danazol on Pituitary Gonadotrophins in Post‐Menopausal Women 1978
- DANAZOL: AN ANTIGONADOTROPHIC AGENT IN THE TREATMENT OF RECURRENT PELVIC AND INTESTINAL ENDOMETRIOSIS 1977
- Danazol therapy in hormone-sensitive mammary carcinoma 1977
- Danazol Inhibits Steroidogenesis 1977
- The Effect of Danazol on Anterior Pituitary Function 1977
- Progestational activity of Danazol in the human female subject 1976
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