Danazol and fetal masculinization: a warning

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AI-generated summary by claude@2026-06, 2026-06-09

Danazol use during pregnancy for infertility has been linked to fetal masculinization, necessitating patient awareness and concurrent contraception to prevent exposure.

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Abstract

Masculinization of a female fetus occurred during a pregnancy in which the mother received danazol for infertility due to endometriosis. The biochemical theories and the necessary treatment are outlined. Conception may occur before or during a course of danazol, and patients should be made aware of the need for concomitant contraception.

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Condition tags

endometriosisinfertility

MeSH descriptors

Danazol Disorders of Sex Development Pregnadienes Danazol Disorders of Sex Development Disorders of Sex Development Female Fetus Fetus Genitalia, Female Genitalia, Female Humans Infant Maternal-Fetal Exchange Pregnadienes Pregnancy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (12)

Cited by (3)

Source provenance

europepmc
last seen: 2026-06-21T06:12:49.409960+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:09:40.384591+00:00
License: CC0 · commercial use OK