Danazol and fetal masculinization: a warning
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Danazol use during pregnancy for infertility has been linked to fetal masculinization, necessitating patient awareness and concurrent contraception to prevent exposure.
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Abstract
Masculinization of a female fetus occurred during a pregnancy in which the mother received danazol for infertility due to endometriosis. The biochemical theories and the necessary treatment are outlined. Conception may occur before or during a course of danazol, and patients should be made aware of the need for concomitant contraception.
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References (12)
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- Danazol Inhibits Steroidogenesis via openalex
- Danazol May Cause Female Pseudohermaphroditism via openalex
- Dosage aspects of danazol therapy in endometriosis: Short-term and long-term effectiveness via openalex
- Female pseudohermaphroditism with somatic chromosomal anomaly in association with in utero exposure to danazol via openalex
- Pituitary Gonadotropin Inhibitory Activity of Danazol via openalex
- Transient Adrenogenital Syndrome due to Exposure to Danazol in Utero via openalex
- W2042869007 via openalex
- W1491974427 via openalex
- W2005632323 via openalex
- W2007785687 via openalex
- W2039265676 via openalex
Cited by (3)
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- europepmc
- last seen: 2026-06-21T06:12:49.409960+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:09:40.384591+00:00
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