Danazol

A E Madanes, AMOS E. MADANES, MARTIN FARBER, M Farber
Annals of internal medicine · 1982 · vol. 96(5) , pp. 625–630 · doi:10.7326/0003-4819-96-5-625 · PMID:7041729 · W4239651562
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

Danazol, an impeded androgen, is approved for treating endometriosis and cystic breast disease, with ongoing research revealing its potential for other conditions due to its well-tolerated and reversible side effects.

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Abstract

Danazol, approved 5 years ago for the treatment of pelvic endometriosis, has recently been approved for treating cystic disease of the breast. As the mechanisms of action of this drug are made clear, the clinical syndromes that can be treated by this impeded androgen have increased dramatically. Results of controlled prospective clinical studies on the drug have increased our understanding of the pathophysiology of several poorly understood diseases. Danazol is well tolerated by most patients; the side effects are mild and reversible.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Danazol Pregnadienes alpha 1-Antitrypsin Deficiency Angioedema Angioedema Contraceptive Agents Danazol Danazol Danazol Endometriosis Endometriosis Female Fibrocystic Breast Disease Fibrocystic Breast Disease Gonadotropins Gonadotropins Gynecomastia Gynecomastia Humans Lupus Erythematosus, Systemic

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (60)

Cited by (29)

Source provenance

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