Evidence that danazol inhibits gonadotropin-induced ovarian steroidogenesis at a point distal to gonadotropin-receptor interaction and adenosine 3′,5′ cyclic monophosphate formation
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Danazol was found to inhibit gonadotropin-induced steroidogenesis in the ovary at a step after gonadotropin receptors are activated and cAMP is produced.
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References (21)
- Clinical Studies with an Antigonadotropin-Danazol via openalex
- Danazol: An antigonadotropic agent in the treatment of pelvic endometriosis via openalex
- Danazol—a Synthetic Steroid Derivative with Interesting Physiologic Properties via openalex
- Danazol Inhibits Steroidogenesis via openalex
- Danazol Inhibits Steroidogenesis in the Rat Testis<i>in Vitro</i> via openalex
- Effect of danazol on estradiol-17β and progesterone secretion by porcine ovarian cells in vitro via openalex
- Pituitary and Testicular Function Studies. I. Experience with a New Gonadal Inhibitor, 17α-Pregn-4-en-20-yno-(2,3-d) isoxazol-17-ol (Danazol)<sup>1</sup> via openalex
- Pituitary Gonadotropin Inhibitory Activity of Danazol via openalex
- The effect of danazol in sexual precocity. via openalex
- The effect of danazol in the treatment of chronic cystic mastitis. via openalex
- The use of an impeded androgen—danazol—in the management of benign breast disorders via openalex
- Treatment of endometriosis with an antigonadotropin, Danazol. A laparoscopic and histologic evaluation. via openalex
- doi:10.1016/s0015-0282(16)40577-7 via openalex
- doi:10.1111/j.1469-185x.1977.tb00858.x via openalex
- doi:10.1016/0304-4165(75)90077-x via openalex
- doi:10.1016/0006-291x(78)91017-3 via openalex
- W6649741955 via openalex
- W6716775850 via openalex
- doi:10.1042/bj0620315 via openalex
- doi:10.1016/0304-4165(76)90220-8 via openalex
- doi:10.1073/pnas.67.1.305 via openalex
Cited by (24)
- Danazol 2022
- Thermoregulatory and endocrine effects of a low dose of danazol in postmenopausal women: Interaction with the effect of naloxone 1991
- Effects of an androgenic derivative on pre-established mammary tumours chemically induced in the rat 1991
- Inhibition of Rat Ovarian 3.BETA.-Hydroxysteroid Dehydrogenase (3.BETA.-HSD), 17.ALPHA.-Hydroxylase and 17, 20 Lyase by Progestins and Danazol. 1989
- Danazol concentrations in human ovarian follicular fluid and their relationship to simultaneous serum concentrations 1988
- Plasma and peritoneal fluid levels of CA 125 in women with endometriosis 1988
- Endometriosis 1987
- Endocrine Therapy In Primary and Advanced Breast Cancer 1986
- Danazol inhibits steroidogenesis by the human ovary in vivo 1986
- Direct biphasic effects of danazol on gonadotropin-dependent differentiation of cultured rat granulosa cells 1986
- Inhibition of gonadotropin-releasing hormone receptors in rat anterior pituitary monolayer cell cultures by danazol 1986
- Inhibitory effects of danazol on steroidogenesis in cultured human granulosa cells 1986
- Effects of danazol on steroidogenesis and gonadotropic responsiveness in isolated human preovulatory follicular cells 1986
- Changes in the shbg concentration during danazol treatment 1984
- In vitro effect of danazol on steroidogenesis in developing human follicles 1984
- Endocrine effects of danazol in the treatment of endometriosis 1984
- Danazol treatment of severely symptomatic fibrocystic breast disease and long‐term follow‐up—the Hjørring project 1984
- Influence of danazol on cytoplasmic and nuclear estrogen binding capacity in the uterus 1983
- Effects of danazol on gonadal steroidogenesis in patients with a complete form of testicular feminization 1982
- Danazol: Endocrine consequences in healthy women 1981
- Changes of Prolactin Secretion Following Long-Term Danazol Application 1981
- In Vitro Effect of Danazol on Luteinizing Hormone-Releasing Hormone-Stimulated Luteinizing Hormone Release in Rat Anterior Pituitary Cell Cultures in Vitro * 1981
- Endometriosis--continuing conundrum. 1980
- Endometriosis—continuing conundrum 1980
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