Tumor markers in endometriosis

Abrão MS, Maurício Simões Abrão, M S Abrão, Sérgio Podgaec, S Podgaec, Pinotti JA, J. A. Pinotti, R M de Oliveira, de Oliveira RM
International Journal of Gynecology & Obstetrics · 1999 · vol. 66(1) , pp. 19–22 · doi:10.1016/s0020-7292(99)00046-6 · PMID:10458545 · W2076044586
Other OA: closed CC0 ⤵ 41 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study found that CA 125 concentrations were altered in women with pelvic endometriosis, suggesting it is the only important marker for diagnosing stages III/IV.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVES: The objective of the present study was to determine the concentrations of CA 125, CA 15-3, CA 19-9, carcioembryogenic antigen (CEA), alpha-fetoprotein (AFP) and beta-2 microglobulin (B2MG) in patients with pelvic endometriosis. METHOD: Fifty women were divided into two groups: group A (control) had no endometriosis or other diseases, and group B consisted of 35 women with pelvic endometriosis. All women were submitted to serum determination of CA 125, CA 15-3, CA 19-9, CEA, AFP and B2MG. Samples were collected during the menstrual cycle and 1 week later. RESULTS: Mean CA 125 concentrations were altered in patients with endometriosis, but all 50 patients studied presented normal CEA, AFP and B2MG concentrations. Small variations detected in CA 19-9 and CA 15-3 had no statistical significance. CONCLUSION: CA 125 is the only important marker in the diagnosis of stages III/IV of endometriosis, especially when blood samples for its determination are obtained during the first 3 days of the menstrual cycle.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Biomarkers, Tumor Endometriosis Biomarkers, Tumor Biomarkers, Tumor CA-125 Antigen CA-125 Antigen CA-125 Antigen Endometriosis Endometriosis Endometriosis Endometriosis Female Female Humans Humans Pelvis Pelvis Severity of Illness Index Severity of Illness Index

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (12)

Cited by (43)

Source provenance

europepmc
last seen: 2026-10-16T06:09:50.462052+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T20:59:07.345995+00:00
License: CC0 · commercial use OK