Villar’s Nodule with Multifocal Endometriosis: Case Report

Lukman Yusuf, Muhidin Abdo, S Guo, N Rana, D Braun, R House, H Gebel, C Rotman, W Dmowski, L Lozneanu, D Ciobanu-Apostol, R Balan, I Pvleanu, S Giuc, I Cruntu, C Amalinei, P Parasar, P Ozcan, K Terry, C Bulletti, M Coccia, S Battistoni, A Borini, J Wheeler, D Cramer, S Missmer, J Johnston, H Reid, D Hunter, Alkatout, I Meinhold-Heerlein, J. Keckstein, L Mettler, R Victory, M Diamond, D Johns, E Britila, O Ionescu, D Badiu, C Berceanu, S Vlidireanu, D Pop, C Mehedintu, L Capasso, V Sciascia, G Loiaco, G Guida, F Iarrobino, C Di Lillo, . De Luna, F, H. Lee, Y Park, B Jee, Y Kim, C Suh, S Ein, B Pekta, S Hot, V Mihmanl, I Okoye, O Omiwole, O Adeoye, D Olive, L Schwartz, D Yela, I Quagliato, C Benetti-Pinto, J Sampson, Y Wang, K Nicholes, I Shih, B Smolarz, K Szyo, H Romanowicz, G Matarese, G. De Placido, Y Nikas, C Alviggi, M Hornstein, R Gleason, J Orav, S Haas, A Friedman, M Rein, . Barbieri, R, T. Capezzuoli, S Clemenza, F Sorbi, D Campana, S. Vannuccini, C. Chapron, F Petraglia, G Adamson, H Kafali, H Artuc, N Demir, A Ayamo, J Kuria, M Abrao, S Podgaec, J Pinotti, R De Oliveira, N Johnson, L. Hummelshoj, C Allaire, . Vercellini, P, P Frana, A Lontra, P Fernandes, K Nnoaham, P. Webster, T Hooghe, F de Cicco Nardone, C De Cicco Nardone, . Study, W, L Culley, C Law, N Hudson, E Denny, H Mitchell, M. Baumgarten, N Raine-Fenning
In: Journal of Gynecology & Reproductive Medicine · 2023 · vol. 7(1) · doi:10.33140/jgrm.07.01.05 · W4364375688
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This report details a rare case of umbilical endometriosis (Villar's nodule) co-occurring with multifocal pelvic and peritoneal endometriosis in a patient without a prior diagnosis, highlighting the need for considering endometriosis in patients with relevant symptoms.

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Abstract

Umbilical endometriosis which was first described by Villar in 1886 is a rare clinical entity with a frequency of only 0.5-1%. The overall prevalence rate of endometriosis among women in their reproductive age is put at 5-10%. This is a descriptive presentation of a Villar’s nodule with concurrent multifocal presentations paradoxically affecting the pelvic structures and the peritoneal wall in a patient with no prior history of a diagnosis or treatment for endometriosis. It is worth considering of the diagnosis in any given patient with nodules, cysts, bleeding and pelvic and/or abdominal pain in order to overcome the delayed and/or under diagnosis of the entity. To the best of our knowledge, this is the first ever reported enigmatic case from Ethiopia. It is intended to highlight aspects of issues pertaining to endometriosis and amplify its importance for academicians and practicing physicians in Ethiopia as an increasingly interesting phenomenon; and finally, to contribute to the world literature from our geographic location.

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endometriosis

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