Endometrium from women with endometriosis shows increased proliferation activity
Observational
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⤵ 64 in-corpus citations
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Endometrial tissue from women with endometriosis exhibits elevated proliferation compared to control tissue.
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Abstract
Examination of 631 infertile women, including 434 women with endometriosis and 197 without endometriosis, revealed an increasing incidence of endometrial polyps, especially in the test subjects with endometriosis, and advanced stages of endometriosis. Expression of Ki-67 and Bcl-2 proteins and MTT assay results were significantly higher in endometrium of patients with endometriosis than in patients without endometriosis. These showed increased proliferation activity and cell proliferation markers not only clinically but also pathologically.
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Cited by (50)
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- Nuclear factor IX promotes endometriosis progression through transcriptional activation of tetraspanin-2 2026
- Clinical predictors of postoperative recurrence in ovarian endometrioma: evaluation of follistatin expression 2026
- Single-Cell RNA Sequencing Shows Markedly Elevated Immune Cell Proportions in the Endometrium of Women with Endometriosis-A Narrative Review 2026
- Association between endometriosis and endometrial polyps: a systematic review and meta-analysis 2025
- The interplay between endometriosis and obesity 2025
- Not Just a Bleeding Scar: The Mystery of Cesarean Scar Endometriosis 2025
- An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review 2024
- Interventional Hydrogel Microsphere Controlled‐Releasing Curcumin for Photothermal Therapy against Endometriosis 2024
- Enrichment of cell cycle pathways in progesterone-treated endometrial organoids of infertile women compared to fertile women 2024
- Expression of HIF-1α, Ki67, SMA and E-cadherin in endometriosis, endometrial and ovarian carcinoma 2024
- Genomic Insults and their Redressal in the Eutopic Endometrium of Women with Endometriosis 2023
- Molecular Mechanisms of Endometriosis Revealed Using Omics Data 2023
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- Evaluation of Ki-67 staining index and BRAF mutation in women diagnosed with advanced endometriosis 2023
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- Endometrial causes of recurrent pregnancy losses: endometriosis, adenomyosis, and chronic endometritis 2021
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- Atypical endometriosis is related to a higher recurrence rate 2020
- Multicentric Study on Endometrial Polyps and Endometriosis: Are They True or False Friends? 2020
- Clinical characteristics and pregnancy outcomes of infertile patients with endometriosis and endometrial polyps: A retrospective cohort study 2020
- Mouse model for endometriosis is characterized by proliferation and inflammation but not epithelial-to-mesenchymal transition and fibrosis 2020
- Immunohistochemical expression of estrogen receptor α, Bcl-2 and NF-κB P65 in the polyps of patients with and without endometriosis 2020
- Deregulation of Stemness-Related Genes in Endometriotic Mesenchymal Stem Cells: Further Evidence for Self-Renewal/Differentiation Imbalance 2020
- Genomic Function of Estrogen Receptor β in Endometriosis 2019
- Ontogeny and expression profiles of steroid hormone receptors in a mouse model of endometriosis 2019
- Effect of Dehydrocostus Lactone Isolated from the Roots of Aucklandia lappa on the Apoptosis of Endometriotic Cells and the Alternative Activation of Endometriosis-Associated Macrophages 2019
- Pyrvinium pamoate inhibits proliferation and invasion of human endometriotic stromal cells 2019
- Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67 2018
- Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility 2018
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- Evaluation of the Ki-67 Proliferation Index and Urocortin Expression in Women with Ovarian Endometriomas 2017
- The role of the sympathetic nervous system and semaphorins in the pathogenesis of endometriosis 2016
- Endometrial biomarkers for the non-invasive diagnosis of endometriosis 2016
- Surgery for Benign Gynecological Disorders Improve Endometrium Receptivity 2016
- Demographic and Clinical Features of Endometrial Polyps in Patients with Endometriosis 2016
- Caracterização morfológica da endometriose ovariana 2016
- Activated Hippo/Yes-Associated Protein Pathway Promotes Cell Proliferation and Anti-apoptosis in Endometrial Stromal Cells of Endometriosis 2016
- Ki-67 Expression is Correlated with Cyst Size and Stage of Endometriosis 2016
- Up-regulation of Bcl-2 by CD147 Through ERK Activation Results in Abnormal Cell Survival in Human Endometriosis 2015
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