Endometriosis: not just a benign disease

Marjolein Hermens
In: maastricht university · 2022 · doi:10.26481/dis.20220627mh · W4281387288
dissertation OA: gold CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study investigated the association between endometriosis and ovarian cancer, particularly its clear-cell and endometrioid subtypes, addressing limitations of previous research regarding statistical power and diagnostic accuracy.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This thesis investigated the associations between proven endometriosis or adenomyosis and cancer outcomes in over 133,000 women. Using population-level data, it found that women with proven endometriosis or adenomyosis had an increased risk of developing ovarian or endometrial cancer. The thesis also reported that overall survival after ovarian or endometrial cancer diagnosis was better for women with endometriosis or adenomyosis than for women without, and that after removal of the ovaries in women with endometriosis, the extra-ovarian cancer risk decreased to below population extra-ovarian cancer risk. This paper is centrally about endometriosis and adenomyosis—quantifying their association with ovarian and endometrial cancer risk and survival.

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Abstract

Background: Several studies have suggested that endometriosis is associated with an increased risk of ovarian cancer, especially for clear-cell and endometrioid subtypes. However previous studies lack sufficient power or diagnostic certainty.

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Condition tags

endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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last seen: 2026-06-10T17:14:06.276822+00:00
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