Coexistence of uterine adenomyosis is not associated with a better prognosis in endometrioid-type endometrial cancer

Koray Aslan, Mustafa Erkan Sarı, Hakan Raşit Yalçın, İbrahim Yalçın, Zeliha FIrat Cüylan, Zeliha Fırat Cüylan, Bülent Özdal
Irish journal of medical science · 2020 · vol. 189(3) , pp. 835–842 · doi:10.1007/s11845-020-02172-z · PMID:31970616 · W3001755519
article OA: closed CC0 ⤵ 9 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

Adenomyosis in endometrioid endometrial cancer patients was associated with earlier stages and less aggressive features, but was not an independent prognostic factor for survival.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This retrospective study analyzed medical records from 552 patients with surgically treated endometrioid-type endometrial cancer (2007–2017) to compare clinicopathologic factors and survival outcomes between those with coexisting uterine adenomyosis (n=103) and those without. Patients with adenomyosis had significantly earlier FIGO stage, lower tumor grade, smaller tumors (≤2 cm), less myometrial invasion (<50%), and fewer lymphovascular space invasion on univariate comparisons. Five-year overall survival was similar between groups, while disease-free survival was higher in the adenomyosis group, but adenomyosis did not remain an independent prognostic factor in multivariate analysis. This paper is centrally about adenomyosis in the context of endometrioid-type endometrial cancer, addressing how coexistence of uterine adenomyosis relates to cancer prognosis, which is relevant to adenomyosis research.

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Condition tags

adenomyosis

MeSH descriptors

Endometrial Neoplasms Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adult Aged Aged, 80 and over Endometrial Neoplasms Endometrial Neoplasms Endometrial Neoplasms Female Humans Middle Aged Prognosis Retrospective Studies Survival Rate

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