Association between endometriosis and gynecological cancers: a critical review of the literature

Dimitrios Rafail Kalaitzopoulos, Angeliki Mitsopoulou, Sotiria Maria Iliopoulou, Aris Daniilidis, Angelos Daniilidis, Eleftherios Pierre Samartzis, Eleftherios P Samartzis, Konstantinos P Economopoulos
Archives of gynecology and obstetrics · 2020 · vol. 301(2) , pp. 355–367 · doi:10.1007/s00404-020-05445-1 · PMID:32025845 · W3004676996
review OA: closed CC0 ⤵ 24 in-corpus citations
Limited metadata. Only one source feed has indexed this record so far — no abstract, full text, or open-access copy is available through Endo Lab. The publisher's page (linked below) is the canonical location for the actual content. If you have institutional access, use "Find at my library".
View at publisher → View on OpenAlex View on PubMed
⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This review critically presents evidence on endometriosis associations with gynecological cancers, finding support for an ovarian cancer link, particularly endometrioid and clear cell subtypes, but no clear association with endometrial, cervical, or breast cancer.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This critical review examined published human studies assessing whether endometriosis is associated with gynecological cancers, with an emphasis on ovarian cancer, using a search of MEDLINE, EMBASE, and CINAHL for original research in any language. Across included studies, it reports evidence spanning 25 studies on ovarian cancer, 8 on breast cancer, 8 on endometrial cancer, and 2 on cervical cancer. The authors conclude that the literature supports prior evidence for an association between endometriosis and ovarian cancer, particularly the endometrioid and clear cell histologic subtypes, while more recent population-based studies did not show a clear association with endometrial, cervical, or breast cancer. A major caveat stated in the review is that the most recent population-based epidemiological evidence does not provide a clear association beyond ovarian cancer. This paper is centrally about endometriosis — it critically synthesizes evidence linking endometriosis to gynecological cancers, especially ovarian clear cell and endometrioid carcinoma.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Breast Neoplasms Carcinoma, Endometrioid Endometrial Neoplasms Endometriosis Genital Neoplasms, Female Ovarian Neoplasms Uterine Cervical Neoplasms Adult Breast Neoplasms Carcinoma, Endometrioid Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometrium Endometrium Female Genital Neoplasms, Female Gynecology Humans Middle Aged

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (74)

Cited by (24)

Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:22:17.025735+00:00
unpaywall
last seen: 2026-06-13T06:42:57.164913+00:00
License: CC0 · commercial use OK