Endometriosis-associated endometrioid adenocarcinoma of the fallopian tube synchronized with endometrial adenocarcinoma: A case report

Jian-Yang Feng, Jianyang Feng, Qing-Ping Jiang, Qingping Jiang, Hong He
World journal of clinical cases · 2023 · vol. 11(6) , pp. 1365–1371 · doi:10.12998/wjcc.v11.i6.1365 · PMID:36926121 · PMC10013107 · W4321463957
article OA: gold CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This case report describes a rare instance of a 49-year-old woman diagnosed with synchronized endometrioid adenocarcinoma of the fallopian tube and endometrial adenocarcinoma, highlighting diagnostic challenges and the importance of pathological identification.

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Abstract

BACKGROUND: Endometriosis is a common gynecological disorder that affects women of reproductive age. It is characterized by a cancer-like invasion of the extra-uterine endometrium and exhibits a strong association with ovarian clear cell cancer and endometrioid cancer. Endometriosis-associated fallopian tube endometrioid adenocarcinoma synchronized with endometrial adenocarcinoma was rarely reported. CASE SUMMARY: A 49-year-old woman was referred to our hospital complaining about abnormal vaginal bleeding for three years following unsatisfactory medication. Intraoperative frozen sections unexpectedly unveiled an endometrioid cancer of the left fallopian tube with superficial invasion surrounded by diffuse endometriosis synchronized with endometrioid endometrial cancer. CONCLUSION: It was difficult to make a differential diagnosis when confronted with incidental findings of fallopian tube cancer lesions synchronized with endometrial cancer. The key differential diagnosis of primary endometriosis-associated endometrioid adenocarcinoma of the fallopian tube from endometrial adenocarcinoma involvement relies on the pathological identification of malignant transformation in fallopian tube endometriosis disease.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (11)

Cited by (2)

SciLite annotations

organisms 1
noordeloos 2009062
chemicals 7
estrogen estrogen estrogen steroid estrogen estrogen dydrogesterone

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